Pentanamide, 5-bromo-N-(4-methoxyphenyl)-

Base Information

• Chemical Name: Pentanamide, 5-bromo-N-(4-methoxyphenyl)-
• CAS No.: 182887-95-2
• Molecular Formula: C12H16BrNO2
• Molecular Weight: 286.169
• DSSTox Substance ID: DTXSID40455939
• Nikkaji Number: J766.649G
• Wikidata: Q82278116
• Mol file: 182887-95-2.mol

Synonyms:Pentanamide, 5-bromo-N-(4-methoxyphenyl)-;182887-95-2;DTXSID40455939;N-(4-Methoxyphenyl)-5-bromovaleramide

Chemical Property of Pentanamide, 5-bromo-N-(4-methoxyphenyl)-

Chemical Property:

• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 285.03644
• Heavy Atom Count: 16
• Complexity: 203

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)NC(=O)CCCCBr

Technology Process of Pentanamide, 5-bromo-N-(4-methoxyphenyl)-

There total 2 articles about Pentanamide, 5-bromo-N-(4-methoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

5-bromovaleroyl chloride (4509-90-4) + 4-methoxy-aniline (104-94-9) → 5-Bromo-pentanoic acid (4-methoxy-phenyl)-amide (182887-95-2)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 20 ℃; for 3.5h;

DOI:10.1016/S0040-4020(97)00222-6

Reference yield:

5-bromopentanoic acid (2067-33-6) → 5-Bromo-pentanoic acid (4-methoxy-phenyl)-amide (182887-95-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / thionyl chloride / CHCl₃ / 12 h / Heating

2: pyridine / CHCl₃ / 0 - 20 °C

With pyridine; thionyl chloride; In chloroform;

DOI:10.1021/ol052895w

Reference yield: 98.0%

2-amino-4-(trifluoromethyl)benzenethiol hydrochloride (4274-38-8) + 5-Bromo-pentanoic acid (4-methoxy-phenyl)-amide (182887-95-2) → 5-(2-Amino-4-trifluoromethyl-phenylsulfanyl)-pentanoic acid (4-methoxy-phenyl)-amide

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 6h;

DOI:10.1016/0040-4039(96)01419-0

upstream raw materials:

5-bromovaleroyl chloride

4-methoxy-aniline

5-bromopentanoic acid

Downstream raw materials:

N-(4-methoxyphenyl)pentanamide

5-azido-pentanoic acid (4-methoxy-phenyl)-amide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 182887-95-2 Pentanamide, 5-bromo-N-(4-methoxyphenyl)-

Send

Send

Metric Ton KG G Pound L ML

Send

Send