5-Bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine

Base Information

Chemical Name:5-Bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine
CAS No.:183208-22-2
Molecular Formula:C8H7BrN2
Molecular Weight:211.061
Hs Code.:2933990090
DSSTox Substance ID:DTXSID30571112
Wikidata:Q82458725
Mol file:183208-22-2.mol

Synonyms:5-Bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine;183208-22-2;5-BROMO-1-METHYL-7-AZAINDOLE;5-BROMO-1-METHYLPYRROLO[2,3-B]PYRIDINE;MFCD14706089;1H-Pyrrolo[2,3-b]pyridine, 5-bromo-1-methyl-;SCHEMBL857319;DTXSID30571112;FBOBGKHOQSQKRZ-UHFFFAOYSA-N;AKOS016009671;DS-5101;PB24178;SY098604;CS-0043009;5- bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine;EN300-223678;A880840;W-205174;5-Bromo-1-methyl-1H-pyrrolo[2 pound not3-b]pyridine;Z1269215836

Suppliers and Price of 5-Bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine
100mg
$ 60.00

SynQuest Laboratories
5-Bromo-1-methyl-7-azaindole
250 mg
$ 60.00

SynQuest Laboratories
5-Bromo-1-methyl-7-azaindole
1 g
$ 180.00

SynQuest Laboratories
5-Bromo-1-methyl-7-azaindole
5 g
$ 610.00

Matrix Scientific
5-Bromo-1-methyl-7-azaindole
5g
$ 624.00

Matrix Scientific
5-Bromo-1-methyl-7-azaindole
1g
$ 227.00

Crysdot
5-Bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine 95+%
5g
$ 535.00

Chemenu
5-bromo-1-methyl-1h-pyrrolo[2,3-b]pyridine 95%+
250mg
$ 88.00

Chemcia Scientific
5-Bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine 95%
10 G
$ 595.00

Chemcia Scientific
5-Bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine 95%
1 G
$ 120.00

Total 20 raw suppliers

Chemical Property of 5-Bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine

Chemical Property:

Boiling Point:294.3±20.0 °C(Predicted)
PKA:3.11±0.30(Predicted)
PSA：17.82000
Density:1.60±0.1 g/cm3(Predicted)
LogP:2.33580
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:209.97926
Heavy Atom Count:11
Complexity:151

Purity/Quality:

99%, ^*data from raw suppliers

5-Bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C=CC2=CC(=CN=C21)Br

Technology Process of 5-Bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine

There total 8 articles about 5-Bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 183208-35-7
5-bromo-1H-pyrrolo[2,3-b]pyridine

: 74-88-4
methyl iodide

: 183208-22-2
5-bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: 5-bromo-1H-pyrrolo[2,3-b]pyridine; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃;

methyl iodide; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

: 183208-35-7
5-bromo-1H-pyrrolo[2,3-b]pyridine

: 183208-22-2
5-bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: 5-bromo-1H-pyrrolo[2,3-b]pyridine; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 1h; Inert atmosphere;

methyl halide; In tetrahydrofuran; for 1h; regioselective reaction; Inert atmosphere;
DOI:10.1039/c6cc00133e

Reference yield:

: 271-63-6
7-Azaindole

: 183208-22-2
5-bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: Multi-step reaction with 4 steps

1.1: 85 percent / bromine / 2-methyl-propan-2-ol; H₂O / 20 °C

2.1: 94 percent / zinc; acetic acid / 20 °C

3.1: borane*tetrahydrofurane / tetrahydrofuran / 0.58 h / 0 - 20 °C

3.2: 50 percent / manganese triacetate / acetic acid / 0.75 h / 75 °C

4.1: sodium hydride in oil / dimethylformamide / 0.5 h / 0 °C

4.2: 63 percent / dimethylformamide / 12 h / 0 - 20 °C

With borane-THF; bromine; sodium hydride; acetic acid; zinc; In tetrahydrofuran; water; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.3987/COM-02-9695