2(1H)-Pyrazinone, 5,6-dihydro-1-(phenylmethyl)-, 4-oxide

Base Information

Chemical Name:2(1H)-Pyrazinone, 5,6-dihydro-1-(phenylmethyl)-, 4-oxide
CAS No.:183269-83-2
Molecular Formula:C11H12N2O2
Molecular Weight:204.228
Hs Code.:
DSSTox Substance ID:DTXSID80455034
Nikkaji Number:J775.174E
Wikidata:Q82276872
Mol file:183269-83-2.mol

Synonyms:183269-83-2;2(1H)-Pyrazinone, 5,6-dihydro-1-(phenylmethyl)-, 4-oxide;DTXSID80455034;3-Oxo-4-benzyl-3,4,5,6-tetrahydropyrazine 1-oxide

Suppliers and Price of 2(1H)-Pyrazinone, 5,6-dihydro-1-(phenylmethyl)-, 4-oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2(1H)-Pyrazinone, 5,6-dihydro-1-(phenylmethyl)-, 4-oxide

Chemical Property:

XLogP3:-0.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:204.089877630
Heavy Atom Count:15
Complexity:270

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C[N+](=CC(=O)N1CC2=CC=CC=C2)[O-]

Technology Process of 2(1H)-Pyrazinone, 5,6-dihydro-1-(phenylmethyl)-, 4-oxide

There total 4 articles about 2(1H)-Pyrazinone, 5,6-dihydro-1-(phenylmethyl)-, 4-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 59702-21-5
1-benzyl-piperazin-2-one

: 183269-83-2
1-benzyl-4-oxy-5,6-dihydro-1H-pyrazin-2-one

Guidance literature:: With dihydrogen peroxide; sodium tungstate; In ethanol; for 6h;
DOI:10.1055/s-2004-834955

Reference yield:

: 78551-60-7
1-benzyl-4-(tert-butyloxycarbonyl)piperazin-2-one

: 183269-83-2
1-benzyl-4-oxy-5,6-dihydro-1H-pyrazin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / TFA / 0.33 h / 0 °C

2: 70 percent / aq. H₂O₂ / Na₂WO₄*2H₂O / ethanol / 6 h

With dihydrogen peroxide; trifluoroacetic acid; sodium tungstate; In ethanol;
DOI:10.1055/s-2004-834955

Reference yield:

: 100-39-0
benzyl bromide

: 183269-83-2
1-benzyl-4-oxy-5,6-dihydro-1H-pyrazin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 74 percent / NaH / dimethylformamide / 18 h

2: 85 percent / TFA / 0.33 h / 0 °C

3: 70 percent / aq. H₂O₂ / Na₂WO₄*2H₂O / ethanol / 6 h

With dihydrogen peroxide; sodium hydride; trifluoroacetic acid; sodium tungstate; In ethanol; N,N-dimethyl-formamide;
DOI:10.1055/s-2004-834955