4,6-Dichloro-N-methyl-5-(phenylsulfanyl)pyrimidin-2-amine

Base Information

Chemical Name:4,6-Dichloro-N-methyl-5-(phenylsulfanyl)pyrimidin-2-amine
CAS No.:183811-04-3
Molecular Formula:C11H9Cl2N3S
Molecular Weight:286.185
Hs Code.:
DSSTox Substance ID:DTXSID40590874
Nikkaji Number:J1.536.133F
Mol file:183811-04-3.mol

Synonyms:183811-04-3;SCHEMBL8564591;4,6-Dichloro-N-methyl-5-(phenylsulfanyl)pyrimidin-2-amine;DTXSID40590874

Suppliers and Price of 4,6-Dichloro-N-methyl-5-(phenylsulfanyl)pyrimidin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 4,6-Dichloro-N-methyl-5-(phenylsulfanyl)pyrimidin-2-amine

Chemical Property:

XLogP3:4.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:284.9894239
Heavy Atom Count:17
Complexity:227

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CNC1=NC(=C(C(=N1)Cl)SC2=CC=CC=C2)Cl

Technology Process of 4,6-Dichloro-N-methyl-5-(phenylsulfanyl)pyrimidin-2-amine

There total 8 articles about 4,6-Dichloro-N-methyl-5-(phenylsulfanyl)pyrimidin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 74-89-5
methylamine

: 183811-00-9
2,4,6-trichloro-5-phenylthiopyrimidine

: 183811-04-3
2-methylamino-4,6-dichloro-5-phenylthiopyrimidine

: (2,6-dichloro-5-phenylsulfanyl-pyrimidin-4-yl)-methyl-amine

Guidance literature:: In water; butanone; at 5 ℃; for 2h;
DOI:10.1016/S0960-894X(01)00167-6

Reference yield: 40.0%

: 204642-75-1
2-methylamino-5-phenylsulfanyl-pyrimidine-4,6-diol

: 183811-04-3
2-methylamino-4,6-dichloro-5-phenylthiopyrimidine

Guidance literature:: With trichlorophosphate; for 2h; Heating;
DOI:10.1016/S0960-894X(01)00167-6

Reference yield:

: 1193-82-4
racemic methyl phenyl sulfoxide

: 183811-04-3
2-methylamino-4,6-dichloro-5-phenylthiopyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / Ac₂O; AcOH / 2 h / 90 °C

2: 100 percent / POCl₃; dimethyl aniline / 24 h / Heating

3: 80 percent / butan-2-one; H₂O / 2 h / 5 °C

With acetic anhydride; acetic acid; 2,3-Dimethylaniline; trichlorophosphate; In water; butanone;
DOI:10.1016/S0960-894X(01)00167-6