N-ALLOC-1 6-HEXANEDIAMINE HYDROCHLORIDE

Base Information

• Chemical Name: N-ALLOC-1 6-HEXANEDIAMINE HYDROCHLORIDE
• CAS No.: 184292-16-8
• Molecular Formula: C10H20N2O2
• Molecular Weight: 236.73900
• Hs Code.: 2924199090
• Mol file: 184292-16-8.mol

Synonyms:4-allyloxynitrobenzene;allyl 6-aminohexylcarbamate;Allyl p-nitrophenyl ether;O-allyl ether of 4-nitrophenol;Ether,allyl p-nitrophenyl;

Chemical Property of N-ALLOC-1 6-HEXANEDIAMINE HYDROCHLORIDE

Chemical Property:

• PSA: 64.35000
• LogP: 3.31090

Purity/Quality:

98%min ^*data from raw suppliers

Prop-2-en-1-yl N-(6-aminohexyl)carbamate 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-ALLOC-1 6-HEXANEDIAMINE HYDROCHLORIDE

There total 2 articles about N-ALLOC-1 6-HEXANEDIAMINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

1,6-Hexanediamine (124-09-4) + Allyl chloroformate (2937-50-0) → (6-aminohexyl)carbamic acid allyl ester (184292-16-8)

Guidance literature:

In chloroform; at 0 - 20 ℃;

DOI:10.1002/psc.1218

Reference yield: 46.0%

1,6-Hexanediamine (124-09-4) + allyl phenyl carbonate (16308-68-2) → (6-aminohexyl)carbamic acid allyl ester (184292-16-8)

Guidance literature:

In ethanol; at 20 ℃;

DOI:10.1055/s-2002-34859

Reference yield: 73.0%

(6-aminohexyl)carbamic acid allyl ester (184292-16-8) + C73H119NO12SSi3 → [2S-(2β(3Z,5S,6S,7R,9S,11Z,13S,14S,15S,16Z,18S),3β,4β,5α,6α)]-14,18-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-19-{4-[(1,1-dimethylethyl)dimethylsilyl]oxy}tetrahydro-3,5-dimethyl-6-(phenylthio)-2H-pyran-2-yl-6-[(4-methoxyphenyl)methoxy]-9- (184291-86-9)

Guidance literature:

With dmap; In dichloromethane; for 0.166667h; Ambient temperature;

DOI:10.1021/ja961374o

upstream raw materials:

1,6-Hexanediamine

allyl phenyl carbonate

Allyl chloroformate

Downstream raw materials:

[2S-(2β(3Z,5S,6S,7R,9S,11Z,13S,14S,15S,16Z,18S),3β,4β,5α,6α)]-14,18-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-19-{4-[(1,1-dimethylethyl)dimethylsilyl]oxy}tetrahydro-3,5-dimethyl-6-(phenylthio)-2H-pyran-2-yl-6-[(4-methoxyphenyl)methoxy]-9-

C₅₈H₇₈N₈O₉

C₅₈H₇₈N₈O₉

C₅₈H₇₆N₈O₈

Refernces

• 1、 Vaz, Belen,Brunsveld, Luc. "Stable helical peptoids via covalent side chain to side chain cyclization". body text. p. 2988 - 2994. Retrieved 2009/02/03.
• 2、 Pittelkow, Michael,Lewinsky, Rasmus,Christensen, Jorn Bolstad. "Selective synthesis of carbamate protected polyamines using alkyl phenyl carbonates". . p. 2195 - 2202. Retrieved 2007/10/03.