(6E)-6-(morpholin-4-ylmethylidene)-2-phenyl-4,5-dihydro-1,3-benzothiazol-7-one

Base Information

• Chemical Name: (6E)-6-(morpholin-4-ylmethylidene)-2-phenyl-4,5-dihydro-1,3-benzothiazol-7-one
• CAS No.: 80379-64-2
• Molecular Formula: C₁₈H₁₈N₂O₂S
• Molecular Weight: 326.419
• NSC Number: 355927
• DSSTox Substance ID: DTXSID60419578

Synonyms:NSC355927;80379-64-2;DTXSID60419578;NSC-355927

Chemical Property of (6E)-6-(morpholin-4-ylmethylidene)-2-phenyl-4,5-dihydro-1,3-benzothiazol-7-one

Chemical Property:

• Vapor Pressure: 2.78E-11mmHg at 25°C
• Boiling Point: 529.1°Cat760mmHg
• Flash Point: 273.8°C
• Density: 1.345g/cm³
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 326.10889899
• Heavy Atom Count: 23
• Complexity: 470

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2=C(C(=O)C1=CN3CCOCC3)SC(=N2)C4=CC=CC=C4
• Isomeric SMILES: C\1CC2=C(C(=O)/C1=C/N3CCOCC3)SC(=N2)C4=CC=CC=C4

Technology Process of (6E)-6-(morpholin-4-ylmethylidene)-2-phenyl-4,5-dihydro-1,3-benzothiazol-7-one

There total 2 articles about (6E)-6-(morpholin-4-ylmethylidene)-2-phenyl-4,5-dihydro-1,3-benzothiazol-7-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

morpholine (110-91-8,99108-56-2) + 5,6-dihydro-6-hydroxymethylene-2-phenylbenzothiazol-7-(4H)-one → 6-[1-Morpholin-4-yl-meth-(E)-ylidene]-2-phenyl-5,6-dihydro-4H-benzothiazol-7-one (80379-64-2)

Guidance literature:

Reference yield:

(1,2,5-triphenyl-1H-pyrrole-3,4-diyl)bis(phenylmethanone) (13209-36-4) + benzylamine (100-46-9) → 2,4,5,7-tetraphenyl-2H-pyrazolo<4,3-c>pyridine (80379-56-2) + 6-[1-Morpholin-4-yl-meth-(E)-ylidene]-2-phenyl-5,6-dihydro-4H-benzothiazol-7-one (80379-64-2)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; at 140 - 150 ℃; for 15h;

Reference yield: 78.0%

6-[1-Morpholin-4-yl-meth-(E)-ylidene]-2-phenyl-5,6-dihydro-4H-benzothiazol-7-one (80379-64-2) + methanesulfonyl chloride (124-63-0) → 6-Morpholin-4-yl-2-phenyl-4,5,6,7-tetrahydro-9-oxa-1,8-dithia-3-aza-cyclopenta[a]naphthalene 8,8-dioxide (80379-72-2)

Guidance literature:

With triethylamine;

upstream raw materials:

morpholine

(1,2,5-triphenyl-1H-pyrrole-3,4-diyl)bis(phenylmethanone)

benzylamine

Downstream raw materials:

6-Morpholin-4-yl-2-phenyl-4,5,6,7-tetrahydro-9-oxa-1,8-dithia-3-aza-cyclopenta[a]naphthalene 8,8-dioxide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 80379-64-2 (6E)-6-(morpholin-4-ylmethylidene)-2-phenyl-5,6-dihydro-1,3-benzothiazol-7(4H)-one

Send

Send

Metric Ton KG G Pound L ML

Send

Send