10-(3-Chloropropyl)-10H-phenothiazine-2-carbonitrile

Base Information

Chemical Name:10-(3-Chloropropyl)-10H-phenothiazine-2-carbonitrile
CAS No.:63457-22-7
Molecular Formula:C16H13 Cl N2 S
Molecular Weight:300.812
Hs Code.:2934300000
European Community (EC) Number:264-209-0
DSSTox Substance ID:DTXSID50212878
Nikkaji Number:J25.654D
Wikidata:Q83088099

Synonyms:10-(3-Chloropropyl)-10H-phenothiazine-2-carbonitrile;63457-22-7;EINECS 264-209-0;DTXSID50212878

Suppliers and Price of 10-(3-Chloropropyl)-10H-phenothiazine-2-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 10-(3-Chloropropyl)-10H-phenothiazine-2-carbonitrile

Chemical Property:

Vapor Pressure:2.05E-09mmHg at 25°C
Melting Point:135-136 °C
Boiling Point:481.1°C at 760 mmHg
PKA:-2.26±0.20(Predicted)
Flash Point:244.8°C
PSA：52.33000
Density:1.35g/cm³
LogP:4.85488
XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:300.0487973
Heavy Atom Count:20
Complexity:380

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)N(C3=C(S2)C=CC(=C3)C#N)CCCCl

Technology Process of 10-(3-Chloropropyl)-10H-phenothiazine-2-carbonitrile

There total 5 articles about 10-(3-Chloropropyl)-10H-phenothiazine-2-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 38642-74-9
10H-phenothiazine-2-carbonitrile

: 109-70-6
1.3-chlorobromopropane

: 63457-22-7
10-(3'-chloropropyl)-2-cyano-10H-phenothiazine

: C₁₆H₁₃BrN₂S

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 7h; Overall yield = 969 mg;
DOI:10.1021/acs.orglett.8b02528

Reference yield:

: 6940-76-7
1-iodo-3-chloro-propane

: 38642-74-9
10H-phenothiazine-2-carbonitrile

: 63457-22-7
10-(3'-chloropropyl)-2-cyano-10H-phenothiazine

Guidance literature:: 10H-phenothiazine-2-carbonitrile; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

1-iodo-3-chloro-propane; In N,N-dimethyl-formamide; at 0 ℃; for 1h;
DOI:10.1002/asia.201900587