Carbamic acid, [1,1-dimethyl-2-[methyl[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazin yl)phenyl]amino]ethyl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:Carbamic acid, [1,1-dimethyl-2-[methyl[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazin yl)phenyl]amino]ethyl]-, 1,1-dimethylethyl ester
CAS No.:184766-43-6
Molecular Formula:C21H32N4O3
Molecular Weight:388.51
Hs Code.:
Mol file:184766-43-6.mol

Carbamic acid,
[1,1-dimethyl-2-[methyl[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazin
yl)phenyl]amino]ethyl]-, 1,1-dimethylethyl ester

Synonyms:

Suppliers and Price of Carbamic acid, [1,1-dimethyl-2-[methyl[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazin yl)phenyl]amino]ethyl]-, 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Carbamic acid, [1,1-dimethyl-2-[methyl[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazin yl)phenyl]amino]ethyl]-, 1,1-dimethylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Carbamic acid, [1,1-dimethyl-2-[methyl[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazin yl)phenyl]amino]ethyl]-, 1,1-dimethylethyl ester

There total 5 articles about Carbamic acid, [1,1-dimethyl-2-[methyl[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazin yl)phenyl]amino]ethyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 184766-37-8
4-{4-[(2-tert-Butoxycarbonylamino-2-methyl-propyl)-methyl-amino]-phenyl}-3-methyl-4-oxo-butyric acid methyl ester

: 184766-43-6
(1,1-Dimethyl-2-{methyl-[4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)-phenyl]-amino}-ethyl)-carbamic acid tert-butyl ester

Guidance literature:: With hydrazine hydrate; In ethanol; for 3h; Heating;
DOI:10.1248/cpb.44.2061

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 184766-43-6
(1,1-Dimethyl-2-{methyl-[4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)-phenyl]-amino}-ethyl)-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 78.9 percent / H₂O / 1 h / Ambient temperature

2: 86.7 percent / SO₃*pyridine, Et₃N / dimethylsulfoxide / 0.5 h / Ambient temperature

3: 60.2 percent / NaBH₃CN, AcOH / methanol / 2 h

4: 64.9 percent / NaBH₃CN, AcOH / methanol / 10 h / Heating

5: 88 percent / hydrazine hydrate / ethanol / 3 h / Heating

With pyridine-SO₃ complex; sodium cyanoborohydride; hydrazine hydrate; acetic acid; triethylamine; In methanol; ethanol; water; dimethyl sulfoxide;
DOI:10.1248/cpb.44.2061

Reference yield:

: 102520-97-8
2-((tert-butyloxycarbonyl)amino)-2-methylpropan-1-ol

: 184766-43-6
(1,1-Dimethyl-2-{methyl-[4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)-phenyl]-amino}-ethyl)-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 86.7 percent / SO₃*pyridine, Et₃N / dimethylsulfoxide / 0.5 h / Ambient temperature

2: 60.2 percent / NaBH₃CN, AcOH / methanol / 2 h

3: 64.9 percent / NaBH₃CN, AcOH / methanol / 10 h / Heating

4: 88 percent / hydrazine hydrate / ethanol / 3 h / Heating

With pyridine-SO₃ complex; sodium cyanoborohydride; hydrazine hydrate; acetic acid; triethylamine; In methanol; ethanol; dimethyl sulfoxide;
DOI:10.1248/cpb.44.2061