2-Acridinecarboxylic acid

Base Information

• Chemical Name: 2-Acridinecarboxylic acid
• CAS No.: 54328-73-3
• Molecular Formula: C14H9NO2
• Molecular Weight: 223.2268
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID30202696
• Nikkaji Number: J89.858I
• Wikidata: Q83076007
• Mol file: 54328-73-3.mol

Synonyms:2-Acridinecarboxylic acid;54328-73-3;acridine-2-carboxylic acid;Acridine-3-carboxylic acid;BRN 0173258;4-22-00-01323 (Beilstein Handbook Reference);SCHEMBL7565802;DTXSID30202696

Chemical Property of 2-Acridinecarboxylic acid

Chemical Property:

• Vapor Pressure: 9.21E-09mmHg at 25°C
• Boiling Point: 446.7°Cat760mmHg
• Flash Point: 223.9°C
• PSA: 50.19000
• Density: 1.366g/cm³
• LogP: 3.08620
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 223.063328530
• Heavy Atom Count: 17
• Complexity: 305

Purity/Quality:

ACRIDINE-2-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=C3C=C(C=CC3=N2)C(=O)O

Technology Process of 2-Acridinecarboxylic acid

There total 1 articles about 2-Acridinecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

9-oxo-9,10-dihydro-acridine-2-carboxylic acid (42946-36-1) → acridine-2-carboxylic acid (54328-73-3)

Guidance literature:

With aluminium amalgam; water; Erhitzen des mit wss. HCl angesaeuerten Reaktionsgemisches mit FeCl₃;

DOI:10.1039/jr9460000706

Reference yield:

acridine-2-carboxylic acid (54328-73-3) + N,N-dimethylethylenediamine (108-00-9) → Acridine-2-carboxylic acid (2-dimethylamino-ethyl)-amide (106626-56-6)

Guidance literature:

With 1,1'-carbonyldiimidazole; Yield given. Multistep reaction; 1.) DMF, 20 deg C, 2.) DMF, 0 deg C, 5 min;

DOI:10.1021/jm00387a014

upstream raw materials:

9-oxo-9,10-dihydro-acridine-2-carboxylic acid

Downstream raw materials:

Acridine-2-carboxylic acid (2-dimethylamino-ethyl)-amide