2-Quinoxalinecarboxamide, N-(2-hydroxy-1-methyl-2-phenylethyl)-N,3-dimethyl-, 1,4-dioxide, (R-(R,S))-

Base Information

Chemical Name:2-Quinoxalinecarboxamide, N-(2-hydroxy-1-methyl-2-phenylethyl)-N,3-dimethyl-, 1,4-dioxide, (R-(R*,S*))-
CAS No.:81485-17-8
Molecular Formula:C₂₀H₂₁N₃O₄
Molecular Weight:367.404
Hs Code.:
DSSTox Substance ID:DTXSID00231135
Wikidata:Q83111962
Mol file:81485-17-8.mol

Synonyms:81485-17-8;DTXSID00231135;2-Quinoxalinecarboxamide, N-(2-hydroxy-1-methyl-2-phenylethyl)-N,3-dimethyl-, 1,4-dioxide, (R-(R*,S*))-

Suppliers and Price of 2-Quinoxalinecarboxamide, N-(2-hydroxy-1-methyl-2-phenylethyl)-N,3-dimethyl-, 1,4-dioxide, (R-(R*,S*))-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Quinoxalinecarboxamide, N-(2-hydroxy-1-methyl-2-phenylethyl)-N,3-dimethyl-, 1,4-dioxide, (R-(R*,S*))-

Chemical Property:

PSA：91.46000
LogP:3.19930
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:367.15320616
Heavy Atom Count:27
Complexity:614

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C([N+](=O)C2=CC=CC=C2N1[O-])C(=O)N(C)C(C)C(C3=CC=CC=C3)O
Isomeric SMILES:CC1=C([N+](=O)C2=CC=CC=C2N1[O-])C(=O)N(C)[C@@H](C)[C@@H](C3=CC=CC=C3)O

Technology Process of 2-Quinoxalinecarboxamide, N-(2-hydroxy-1-methyl-2-phenylethyl)-N,3-dimethyl-, 1,4-dioxide, (R-(R*,S*))-

There total 2 articles about 2-Quinoxalinecarboxamide, N-(2-hydroxy-1-methyl-2-phenylethyl)-N,3-dimethyl-, 1,4-dioxide, (R-(R*,S*))- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 90-81-3,7009-81-6,90-83-5,6912-63-6
ephedrine

: 81485-17-8
3-Methyl-1,4-dioxy-quinoxaline-2-carboxylic acid (2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 0 - 5 °C

2: Et₃N / methanol / Ambient temperature

With triethylamine; In methanol;
DOI:10.1021/je00036a039