DIETHYL 2-(2-NITROBENZYL)MALONATE

Base Information

• Chemical Name: DIETHYL 2-(2-NITROBENZYL)MALONATE
• CAS No.: 59803-35-9
• Molecular Formula: C14H17NO6
• Molecular Weight: 295.292
• Hs Code.: 2917399090
• Mol file: 59803-35-9.mol

Synonyms:diethyl 2-nitrobenzylmalonate;(2-Nitro-benzyl)-malonsaeure-diaethylester;Diethyl 2-(2-nitrobenzyl)malonate;2-(2-Nitrobenzyl)malonic acid diethyl ester;(2-nitro-benzyl)-malonic acid diethyl ester;diethyl (2-nitrophenylmethyl)-1,3-propanedioate;

Chemical Property of DIETHYL 2-(2-NITROBENZYL)MALONATE

Chemical Property:

• Vapor Pressure: 3.43E-06mmHg at 25°C
• Boiling Point: 386.9°Cat760mmHg
• Flash Point: 150.4°C
• PSA: 98.42000
• Density: 1.227g/cm³
• LogP: 2.40290
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

Diethyl 2-(2-nitrobenzyl)malonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DIETHYL 2-(2-NITROBENZYL)MALONATE

There total 7 articles about DIETHYL 2-(2-NITROBENZYL)MALONATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

2-nitrophenylmethyl bromide (3958-60-9) + diethyl malonate (105-53-3) → (2-nitro-benzyl)-malonic acid diethyl ester (59803-35-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 2h; Inert atmosphere;

Reference yield:

18-crown-6 ether (17455-13-9) + 2-nitrobenzyl chloride (612-23-7) → (2-nitro-benzyl)-malonic acid diethyl ester (59803-35-9)

Guidance literature:

With potassium carbonate; In hexane;

Reference yield:

18-crown-6 ether (17455-13-9) + 2-nitrobenzyl chloride (612-23-7) + diethyl malonate (105-53-3) → (2-nitro-benzyl)-malonic acid diethyl ester (59803-35-9)

Guidance literature:

With potassium carbonate; In hexane;

upstream raw materials:

ethanol

(2-nitro-benzyl)-malonic acid

2-nitrobenzyl chloride

diethyl malonate

Downstream raw materials:

(2-nitro-benzyl)-malonic acid

3-(2-nitrophenyl)propionic acid

C₂₄H₃₇NO₇Si

3-(2-nitro-phenyl)-propionyl chloride