Aminoacetone hydrochloride

Base Information

• Chemical Name: Aminoacetone hydrochloride
• CAS No.: 7737-17-9
• Molecular Formula: C3H7 N O . Cl H
• Molecular Weight: 109.556
• Hs Code.: 2922399090
• European Community (EC) Number: 231-798-0
• NSC Number: 159195
• DSSTox Substance ID: DTXSID80228088
• Mol file: 7737-17-9.mol

Synonyms:1-aminopropanone;aminoacetone;aminoacetone hydrochloride

Chemical Property of Aminoacetone hydrochloride

Chemical Property:

• Vapor Pressure: 15.1mmHg at 25°C
• Melting Point: 73-74 °C
• Boiling Point: 120.6°Cat760mmHg
• Flash Point: 26.8°C
• PSA: 43.09000
• Density: 0.926g/cm³
• LogP: 1.03640
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 109.0294416
• Heavy Atom Count: 6
• Complexity: 42.2

Purity/Quality:

98%, ^*data from raw suppliers

1-AminoacetoneHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)CN.Cl
• Description: Aminoacetone is a threonine and glycine catabolite that can be converted to methylglyoxal by amine oxidases. It has been identified as one of several endogenous sources of methylglyoxal found in the plasma of diabetes patients. As a pro-oxidant, 0.10-5 mM aminoacetone can induce cell death in RINm5f pancreatic β-cells. Aminoacetone is used as a growth substrate for Pseudomonas.

Technology Process of Aminoacetone hydrochloride

There total 17 articles about Aminoacetone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(2-oxopropyl)carbamic acid benzyl ester (111491-97-5) → 1-aminopropan-2-one hydrochloride (7737-17-9)

Guidance literature:

With hydrogenchloride; hydrogen; palladium 10% on activated carbon; In ethanol; water; at 20 ℃; for 4h;

Reference yield: 100.0%

(+/-)-1-(N-tert-Butoxycarbonylamino)propan-2-one (170384-29-9) → 1-aminopropan-2-one hydrochloride (7737-17-9)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; for 12h;

Reference yield: 99.0%

(R)-N-tert-butanesulfinyl 2,2-diethoxypropylamine (1386376-67-5) → 1-aminopropan-2-one hydrochloride (7737-17-9)

Guidance literature:

With hydrogenchloride; In methanol; at 20 ℃; for 1h;

DOI:10.1021/jo300752c

upstream raw materials:

methanol

N,N-dichloroisopropylamine

sodium methylate

N,N-diformylaminoacetone

Downstream raw materials:

4-methyl-1,3-dihydro-imidazole-2-thione

(+/-)-1-amino-2-phenylpropan-2-ol

benzamidoacetone

5-methyl-2-phenyloxazole