111491-97-5

Basic information

• Product Name: Benzyl 2-oxopropylcarbamate
• Synonyms: Benzyl 2-oxopropylcarbamate
• CAS NO: 111491-97-5
• Molecular Weight: 207.229
• Mol File: 111491-97-5.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzyl 2-oxopropylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: Benzyl 2-oxopropylcarbamate(111491-97-5)
• EPA Substance Registry System: Benzyl 2-oxopropylcarbamate(111491-97-5)

Safety Data

• Hazardous Substances Data: 111491-97-5(Hazardous Substances Data)

Usage

General Description

Benzyl 2-oxopropylcarbamate is a chemical compound that belongs to the class of organic compounds known as carbamates. Carbamates are organic compounds containing a functional group derived from carbamic acid. Although not much information is available about this specific chemical, similar chemicals in its group are used across various industries from medicine to agriculture. However, as with most chemicals in these categories, it is essential to handle them correctly and adhere to safety guidelines owing to their potential toxicity.

Upstream product

• 67865-73-0 Z-ClyCH₂Cl 
• 501-53-1 benzyl chloroformate 
• 5041-33-8 N-(Benzyloxycarbonyl)allylamine 
• 105258-93-3 N-(Benzyloxycarbonyl)azetidin-3-one 
• 67865-70-7 1-diazo-3-(N-benzyloxycarbonyl)amino-2-propanone 
• 65935-10-6 1-Benzyloxycarbonylamino-2,4-propanediol 
• 121505-94-0 N-benzyloxycarbonyl-glycine-N'-methoxy-N'-methylamide 
• 1138-80-3 N-(Benzyloxycarbonyl)glycine 

Downstream Products

• 1449145-62-3 C₁₃H₁₆N₂O₅ 
• 1449145-44-1 C₁₃H₁₆N₂O₅ 
• 1449145-47-4 C₂₉H₄₂N₈O₁₁ 
• 1449145-48-5 C₁₉H₂₄N₄O₇Pd 
• 1449145-49-6 C₁₈H₂₃N₅O₆Pd 
• 1449145-59-8 C₁₄H₁₈N₂O₅ 
• 1449145-60-1 C₁₃H₁₇N₃O₄ 
• 1449145-45-2 C₁₉H₂₆N₄O₇ 
• 1449145-61-2 C₁₈H₂₄N₄O₇ 
• 1449145-46-3 C₁₈H₂₅N₅O₆ 
• 463967-83-1 benzyl N-[(2S)-2-hydroxypropyl]carbamate 
• 130793-70-3 (2R)-N-benzyloxycarbonyl-2-hydroxypropylamine 
• 1320361-81-6 4-(2-(((benzyloxy)carbonyl)amino)acetamido)butanoic acid 
• 33062-43-0 methyl 4-(2-(((benzyloxy)carbonyl)amino)acetamido)butanoate 

Relevant articles and documents

CHEMICAL COMPOUNDS

A compound of formula (I), wherein Ar1, R21, R23, R24, R25, R26, R27, A, X, Y and W are as defined herein. The compounds of the present invention are inhibitors of hematopoietic prostaglandin D synthase (H-PGDS) and can be useful in the treatment of Duchenne muscular dystrophy. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting H-PGDS activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.

A Straightforward Deracemization of sec-Alcohols Combining Organocatalytic Oxidation and Biocatalytic Reduction

An efficient organocatalytic oxidation of racemic secondary alcohols, mediated by sodium hypochlorite (NaOCl) and 2-azaadamantane N-oxyl (AZADO), has been conveniently coupled with a highly stereoselective bioreduction of the intermediate ketone, catalyzed by ketoreductases, in aqueous medium. The potential of this one-pot two-step deracemization process has been proven by a large set of structurally different secondary alcohols. Reactions were carried out up to 100 mm final concentration enabling the preparation of enantiopure alcohols with very high isolated yields (up to 98 %). When the protocol was applied to the stereoisomeric rac/meso mixture of diols, these were obtained with very high enantiomeric excesses and diastereomeric ratios (95 % yield, >99 % ee, >99: 1 dr).

Metallo-foldamers with backbone-coordinative oxime peptides: Control of secondary structures

A new series of square-planar PdII-mediated foldamers with mononuclear and dinuclear helix or (double) hairpin structures were constructed by novel backbonecoordinative oxime peptides. Some of these metallo-foldamers allow significant structura