3-bromo-1-[2-(4-fluorophenyl)-2-oxoethyl]pyridinium

Base Information

• Chemical Name: 3-bromo-1-[2-(4-fluorophenyl)-2-oxoethyl]pyridinium
• CAS No.: 366-64-3
• Molecular Formula: C13H10 Br F N O . Br
• Molecular Weight: 295.1265
• Mol file: 366-64-3.mol

Synonyms:Pyridinium,3-bromo-1-(p-fluorophenacyl)-, bromide (8CI); Pyridinium, 3-bromo-1-[2-(4-fluorophenyl)-2-oxoethyl]-,bromide (9CI); NSC 402751

Chemical Property of 3-bromo-1-[2-(4-fluorophenyl)-2-oxoethyl]pyridinium

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-bromo-1-[2-(4-fluorophenyl)-2-oxoethyl]pyridinium

There total 1 articles about 3-bromo-1-[2-(4-fluorophenyl)-2-oxoethyl]pyridinium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-Bromopyridine (626-55-1,163928-56-1) + 2-bromo-4'-fluoroacetophenone (403-29-2) → 3-bromo-1-(4-fluoro-phenacyl)-pyridinium; bromide (366-64-3)

Guidance literature:

DOI:10.1021/ja01151a501

Reference yield:

3-bromo-1-(4-fluoro-phenacyl)-pyridinium; bromide (366-64-3) + benzalacetophenone (94-41-7) → C28H21BrFNO2

Guidance literature:

With C₃₁H₄₄N₄O₄; potassium carbonate; scandium tris(trifluoromethanesulfonate); In dichloromethane; at 30 ℃; for 12h; stereoselective reaction; Darkness; Inert atmosphere; Glovebox;

DOI:10.1021/jacs.0c07066

Reference yield:

3-bromo-1-(4-fluoro-phenacyl)-pyridinium; bromide (366-64-3) + benzalacetophenone (94-41-7) → C28H21BrFNO2

Guidance literature:

With potassium carbonate; In dichloromethane; at 30 ℃; for 12h; Darkness; Inert atmosphere; Glovebox;

DOI:10.1021/jacs.0c07066

upstream raw materials:

3-Bromopyridine

2-bromo-4'-fluoroacetophenone

Refernces

• 1、 Zhang, Dong,Dong, Shunxi,He, Qianwen,Luo, Yao,Liu, Yun,Liu, Xiaohua,Feng, Xiaoming. "Enantioselective dicarbofunctionalization of (: E)-alkenyloxindoles with pyridinium salts by chiral Lewis acid/photo relay catalysis". supporting information. p. 12757 - 12760. Retrieved 2020/11/02.