2-Bromo-1-(4-fluorophenyl)ethanone

Base Information

Chemical Name:2-Bromo-1-(4-fluorophenyl)ethanone
CAS No.:403-29-2
Molecular Formula:C8H6BrFO
Molecular Weight:217.037
Hs Code.:29147000
European Community (EC) Number:206-955-1
NSC Number:88343
UNII:N3PVV2GVQ8
DSSTox Substance ID:DTXSID20193307
Nikkaji Number:J213.657K
Wikidata:Q72455646
ChEMBL ID:CHEMBL317046
Mol file:403-29-2.mol

Synonyms:(18F) 4-fluorophenacyl bromide;4-fluorophenacyl bromide

Suppliers and Price of 2-Bromo-1-(4-fluorophenyl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Bromo-4’-fluoroacetophenone
25g
$ 210.00

TRC
2-Bromo-4’-fluoroacetophenone
10g
$ 120.00

TCI Chemical
2-Bromo-4'-fluoroacetophenone >97.0%(GC)
5g
$ 41.00

TCI Chemical
2-Bromo-4'-fluoroacetophenone >97.0%(GC)
25g
$ 122.00

SynQuest Laboratories
4-Fluorophenacyl bromide 97%
100 g
$ 93.00

SynQuest Laboratories
4-Fluorophenacyl bromide 97%
5 g
$ 20.00

SynQuest Laboratories
4-Fluorophenacyl bromide 97%
25 g
$ 48.00

Sigma-Aldrich
2-Bromo-4′-fluoroacetophenone 97%
5g
$ 54.60

Sigma-Aldrich
2-Bromo-4′-fluoroacetophenone 97%
25g
$ 42.00

Matrix Scientific
2-Bromo-4'-fluoroacetophenone 97%
25g
$ 22.00

Total 101 raw suppliers

Chemical Property of 2-Bromo-1-(4-fluorophenyl)ethanone

Chemical Property:

Appearance/Colour:beige to light grey-green cryst. powder or flakes
Melting Point:47-49 °C(lit.)
Refractive Index:1.5450 (estimate)
Boiling Point:251.9 °C at 760 mmHg
Flash Point:106.1 °C
PSA：17.07000
Density:1.568 g/cm³
LogP:2.40330
Storage Temp.:Keep Cold
Sensitive.:Lachrymatory
Solubility.:Soluble in methanol.
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:215.95861
Heavy Atom Count:11
Complexity:141

Purity/Quality:

99% ^*data from raw suppliers

2-Bromo-4’-fluoroacetophenone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi, C
Hazard Codes:C,Xi
Statements: 34
Safety Statements: 26-36/37/39-45-27

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=O)CBr)F
Uses 2-Bromo-4’fluoroacetophenone is a intermediate in the synthetic preparation of competitive inhibitors of aromatase. 2-Bromo-4'-fluoroacetophenone is used as an organic chemical synthesis intermediate.

Technology Process of 2-Bromo-1-(4-fluorophenyl)ethanone

There total 15 articles about 2-Bromo-1-(4-fluorophenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 403-42-9
1-(4-fluorophenyl)ethanone

: 403-29-2
2-bromo-4'-fluoroacetophenone

Guidance literature:: With bromine; In 1,4-dioxane; diethyl ether; for 0.5h; Ambient temperature;

Reference yield: 93.0%

: 95895-33-3
1-(bromoethynyl)-4-fluorobenzene

: 403-29-2
2-bromo-4'-fluoroacetophenone

Guidance literature:: With 2-(dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl Au bis(trifluoromethylsulfonyl)imide; water; In 1,2-dichloro-ethane; at 20 ℃; for 14h;
DOI:10.1021/jo401437w