2-((4-Methoxyphenyl)imino)-1-pyrrolidineacetamide monohydrochloride

Base Information

Chemical Name:2-((4-Methoxyphenyl)imino)-1-pyrrolidineacetamide monohydrochloride
CAS No.:91417-85-5
Molecular Formula:C₁₃H₁₇N₃O₂*ClH
Molecular Weight:283.758
Hs Code.:
ChEMBL ID:CHEMBL3209922

Synonyms:1-Carbamidomethyl-2-(N-(p-anisidino)imino)pyrrolidine hydrochloride;2-((4-Methoxyphenyl)imino)-1-pyrrolidineacetamide monohydrochloride;1-Pyrrolidineacetamide, 2-((4-methoxyphenyl)imino)-, monohydrochloride;91417-85-5;SMR000033802;MLS000047797;CHEMBL3209922;LS-137070;SR-01000484131;SR-01000484131-1;2-{(2E)-2-[(4-methoxyphenyl)imino]pyrrolidin-1-yl}acetamide

Suppliers and Price of 2-((4-Methoxyphenyl)imino)-1-pyrrolidineacetamide monohydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-((4-Methoxyphenyl)imino)-1-pyrrolidineacetamide monohydrochloride

Chemical Property:

Vapor Pressure:1.03E-08mmHg at 25°C
Boiling Point:462°Cat760mmHg
Flash Point:233.2°C
Density:g/cm³
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:283.1087545
Heavy Atom Count:19
Complexity:322

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)N=C2CCCN2CC(=O)N.Cl

Technology Process of 2-((4-Methoxyphenyl)imino)-1-pyrrolidineacetamide monohydrochloride

There total 5 articles about 2-((4-Methoxyphenyl)imino)-1-pyrrolidineacetamide monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 64-18-6
formic acid

: 91417-94-6
1-Cyanomethyl-2-pyrrolidine

: 91417-85-5
1-Carbamidomethyl-2-pyrrolidine hydrochloride

Guidance literature:: With hydrogenchloride; Ambient temperature;
DOI:10.1007/BF00758995

Reference yield:

: 57275-83-9
nitrile of 2-oxopyrrolidine-1-acetic acid

: 91417-85-5
1-Carbamidomethyl-2-pyrrolidine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) POCl₃ / 1.) benzene, room temp., 4.5 h, 2.) EtOH, 0.5 h

2: 96 percent / xylene / 6 h / 85 - 90 °C

3: 70 percent / HCl / Ambient temperature

With hydrogenchloride; trichlorophosphate; In xylene;
DOI:10.1007/BF00758995

Reference yield:

: 7491-74-9
2-oxo-1-pyrrolidine acetamide

: 91417-85-5
1-Carbamidomethyl-2-pyrrolidine hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) POCl₃, DMF, 2.) pyridine / 1.) acetonitrile, 50 deg C, 2.5 h, 2.) 0 deg C, 20 min

2: 1.) POCl₃ / 1.) benzene, room temp., 4.5 h, 2.) EtOH, 0.5 h

3: 96 percent / xylene / 6 h / 85 - 90 °C

4: 70 percent / HCl / Ambient temperature

With pyridine; hydrogenchloride; N,N-dimethyl-formamide; trichlorophosphate; In xylene;
DOI:10.1007/BF00758995