N-(3-methoxyphenyl)-4-methylquinolin-2-amine

Base Information

Chemical Name:N-(3-methoxyphenyl)-4-methylquinolin-2-amine
CAS No.:5657-52-3
Molecular Formula:C7H5 N O2
Molecular Weight:135.122
Hs Code.:
DSSTox Substance ID:DTXSID20972013
Wikidata:Q82955715
ChEMBL ID:CHEMBL1502698
Mol file:5657-52-3.mol

Synonyms:N-(3-methoxyphenyl)-4-methylquinolin-2-amine;ChemDiv3_006985;Oprea1_435869;Oprea1_482255;MLS001198563;CHEMBL1502698;DTXSID20972013;HMS1492N11;HMS2883D24;STL431269;AKOS000444250;IDI1_024895;SMR000558984;SR-01000115475;N-(3-Methoxyphenyl)-4-methylquinolin-2(1H)-imine;SR-01000115475-1

Suppliers and Price of N-(3-methoxyphenyl)-4-methylquinolin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
FURO[3,4-C]PYRIDIN-3(1H)-ONE 95.00%
5MG
$ 500.95

AccelPharmtech
Furo[3,4-c]pyridin-3(1H)-one 97.00%
25G
$ 12900.00

AccelPharmtech
Furo[3,4-c]pyridin-3(1H)-one 97.00%
5G
$ 6840.00

AccelPharmtech
Furo[3,4-c]pyridin-3(1H)-one 97.00%
1G
$ 3960.00

Total 7 raw suppliers

Chemical Property of N-(3-methoxyphenyl)-4-methylquinolin-2-amine

Chemical Property:

Vapor Pressure:2.24E-07mmHg at 25°C
Boiling Point:423.4°Cat760mmHg
Flash Point:209.9°C
PSA：39.19000
Density:1.184g/cm³
LogP:0.75200
XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:264.126263138
Heavy Atom Count:20
Complexity:309

Purity/Quality:

99% ^*data from raw suppliers

FURO[3,4-C]PYRIDIN-3(1H)-ONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NC2=CC=CC=C12)NC3=CC(=CC=C3)OC

Technology Process of N-(3-methoxyphenyl)-4-methylquinolin-2-amine

There total 3 articles about N-(3-methoxyphenyl)-4-methylquinolin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

: 4664-08-8
cinchomeronic anhydride

: 5657-52-3
1,3-dihydrofuro<3,4-c>pyridin-3-one

Guidance literature:: cinchomeronic anhydride; With sodium tetrahydroborate; In N,N-dimethyl-formamide; toluene; at -20 - 35 ℃;

With hydrogenchloride; In water; Reflux;
DOI:10.1021/acs.jmedchem.5b00303

Reference yield: 2.0%

: 67-56-1
methanol

: 98-92-0,1255150-40-3
nicotinamide

: 5657-51-2
7H-furo[3,4-b]pyridin-5-one

: 5657-52-3
1,3-dihydrofuro<3,4-c>pyridin-3-one

Guidance literature:: With ammonium persulfate; sulfuric acid; for 0.5h; Heating;
DOI:10.1246/bcsj.55.3055

Reference yield:

: 4664-08-8
cinchomeronic anhydride

: 5657-52-3
1,3-dihydrofuro<3,4-c>pyridin-3-one

: 4741-42-8
furo<3,4-c>pyridin-1(3H)-one

Guidance literature:: With hydrogenchloride; sodium tetrahydroborate; Yield given. Multistep reaction. Yields of byproduct given; 1) DMF, 2) reflux;
DOI:10.1016/S0040-4039(00)92055-0