15-hydroperoxyabietic acid

Base Information

Chemical Name:15-hydroperoxyabietic acid
CAS No.:113903-96-1
Molecular Formula:C₂₀H₃₀O₄
Molecular Weight:334.456
Hs Code.:

Synonyms:1-Phenanthrenecarboxylicacid,1,2,3,4,4a,4b,5,6,10,10a-decahydro-7-(1-hydroperoxy-1-methylethyl)-1,4a-dimethyl-,[1R-(1a,4ab,4ba,10aa)]-; 15-Hydroperoxyabietic acid

Suppliers and Price of 15-hydroperoxyabietic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 15-hydroperoxyabietic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:461.3°Cat760mmHg
Flash Point:156.9°C
PSA：66.76000
Density:1.12g/cm³
LogP:4.81840

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 15-hydroperoxyabietic acid

There total 7 articles about 15-hydroperoxyabietic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 101821-23-2
15-hydroxyabietic acid

: 113903-96-1
7-(1-hydroperoxy-1-methyl-ethyl)-1,4a-dimethyl-1,2,3,4,4a,4b,5,6,10,10a-decahydro-phenanthrene-1-carboxylic acid

Guidance literature:: With sulfuric acid; dihydrogen peroxide; In dichloromethane; at 0 ℃; for 10h;
DOI:10.1055/s-2001-18089

Reference yield:

: 20085-81-8
13-Oxopodocarp-8⁽¹⁴⁾-en-18-saeure-methylester

: 113903-96-1
7-(1-hydroperoxy-1-methyl-ethyl)-1,4a-dimethyl-1,2,3,4,4a,4b,5,6,10,10a-decahydro-phenanthrene-1-carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: 80 percent / t-BuOK / dimethylsulfoxide / 0.75 h / 20 °C

2.1: 74 percent / (COBr)2; DMF / CH₂Cl₂ / 5.25 h / -78 - 20 °C

3.1: t-BuLi / diethyl ether; pentane / 1.5 h / -78 °C

3.2: 70 percent / diethyl ether; pentane / 2 h / 20 °C

4.1: 63 percent / aq. H₂O₂; H₂SO₄ / CH₂Cl₂ / 10 h / 0 °C

With Oxalyl bromide; sulfuric acid; potassium tert-butylate; dihydrogen peroxide; tert.-butyl lithium; N,N-dimethyl-formamide; In diethyl ether; dichloromethane; dimethyl sulfoxide; pentane;
DOI:10.1055/s-2001-18089

Reference yield:

: 19402-34-7
methyl abieta-8,13⁽¹⁵⁾-dien-18-oate

: 113903-96-1
7-(1-hydroperoxy-1-methyl-ethyl)-1,4a-dimethyl-1,2,3,4,4a,4b,5,6,10,10a-decahydro-phenanthrene-1-carboxylic acid

Guidance literature:: Multi-step reaction with 7 steps

1.1: 90 percent / MCPBA / CH₂Cl₂ / 2 h / 0 °C

2.1: 87 percent / H₅IO₆ / tetrahydrofuran / 1 h / -30 - -10 °C

3.1: 96 percent / HCl / methanol / 4 h / 0 °C

4.1: 80 percent / t-BuOK / dimethylsulfoxide / 0.75 h / 20 °C

5.1: 74 percent / (COBr)2; DMF / CH₂Cl₂ / 5.25 h / -78 - 20 °C

6.1: t-BuLi / diethyl ether; pentane / 1.5 h / -78 °C

6.2: 70 percent / diethyl ether; pentane / 2 h / 20 °C

7.1: 63 percent / aq. H₂O₂; H₂SO₄ / CH₂Cl₂ / 10 h / 0 °C

With hydrogenchloride; Oxalyl bromide; sulfuric acid; potassium tert-butylate; dihydrogen peroxide; tert.-butyl lithium; periodic acid; N,N-dimethyl-formamide; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; dimethyl sulfoxide; pentane;
DOI:10.1055/s-2001-18089