15-Hydroxyabieta-7,13-dien-18-oic acid

Base Information

Chemical Name:15-Hydroxyabieta-7,13-dien-18-oic acid
CAS No.:101821-23-2
Molecular Formula:C₂₀H₃₀O₃
Molecular Weight:318.456
Hs Code.:

Synonyms:

Suppliers and Price of 15-Hydroxyabieta-7,13-dien-18-oic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ApexBio Technology
15-hydroxy-abietic-acid
5mg
$ 600.00

Total 11 raw suppliers

Chemical Property of 15-Hydroxyabieta-7,13-dien-18-oic acid

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

15-hydroxy-abietic-acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 15-Hydroxyabieta-7,13-dien-18-oic acid

There total 8 articles about 15-Hydroxyabieta-7,13-dien-18-oic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 67-64-1
acetone

: 388120-49-8
7-bromo-1,4a-dimethyl-1,2,3,4,4a,4b,5,6,10,10a-decahydro-phenanthrene-1-carboxylic acid

: 101821-23-2
15-hydroxyabietic acid

Guidance literature:: 7-bromo-1,4a-dimethyl-1,2,3,4,4a,4b,5,6,10,10a-decahydro-phenanthrene-1-carboxylic acid; With tert.-butyl lithium; In diethyl ether; pentane; at -78 ℃; for 1.5h;

acetone; In diethyl ether; pentane; at 20 ℃; for 2h;
DOI:10.1055/s-2001-18089

Reference yield: 17.0%

: 113903-96-1
7-(1-hydroperoxy-1-methyl-ethyl)-1,4a-dimethyl-1,2,3,4,4a,4b,5,6,10,10a-decahydro-phenanthrene-1-carboxylic acid

: 1039118-68-7
13β,15-epoxy-14α-hydroxy-abiet-7-en-19-oic acid

: 5708-85-0,133131-74-5,135414-08-3,63976-69-2
13-oxo-13-deisopropyl-abiet-8⁽¹⁴⁾en-15-oic acid

: 101821-23-2
15-hydroxyabietic acid

Guidance literature:: In water; acetonitrile; for 5h; Heating;
DOI:10.1016/j.tet.2008.04.035

Reference yield:

: 20085-81-8
13-Oxopodocarp-8⁽¹⁴⁾-en-18-saeure-methylester

: 101821-23-2
15-hydroxyabietic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: 80 percent / t-BuOK / dimethylsulfoxide / 0.75 h / 20 °C

2.1: 74 percent / (COBr)2; DMF / CH₂Cl₂ / 5.25 h / -78 - 20 °C

3.1: t-BuLi / diethyl ether; pentane / 1.5 h / -78 °C

3.2: 70 percent / diethyl ether; pentane / 2 h / 20 °C

With Oxalyl bromide; potassium tert-butylate; tert.-butyl lithium; N,N-dimethyl-formamide; In diethyl ether; dichloromethane; dimethyl sulfoxide; pentane;
DOI:10.1055/s-2001-18089