19402-34-7Relevant academic research and scientific papers
New route to 15-hydroxydehydroabietic acid derivatives: Application to the first synthesis of some bioactive abietane and nor-abietane type terpenoids
Alvarez-Manzaneda,Chahboun,Guardia,Lachkar,Dahdouh,Lara,Messouri
, p. 2577 - 2580 (2006)
A new route to 15-hydroxydehydroabietic acid derivatives from abietic acid (11), via abieta-8,13(15)-dien-18-oic acid (12), is reported. Utilizing this, the first synthesis of bioactive terpenes 3, 6, 9 and 10, as well as natural diol 4 and lactones 7-8 was achieved.
Synthesis and biological evaluation of abietic acid derivatives
Gonzalez, Miguel A.,Correa-Royero, Julieth,Agudelo, Lee,Mesa, Ana,Betancur-Galvis, Liliana
experimental part, p. 2468 - 2472 (2009/12/03)
A series of C18-oxygenated derivatives of abietic acid were synthesized and evaluated for their cytotoxic, antimycotic, and antiviral activities. In general, the introduction of an aldehyde group at C18 did improve the resultant bioactivity, while the presence of an acid or alcohol led to less active compounds.
Conversion of Abietic Acid into Analogues of Ambergris Odorants
Cambie, Richard C.,Rutledge, Peter S.,Ryan, Glen R.,Strange, Gary A.,Woodgate, Paul D.
, p. 867 - 881 (2007/10/02)
The conversion of methyl abietate (16) into (42) and (43), analogues of the known amber odorants (1) and (2), is reported.
SYNTHESIS OF (+)-PODOCARP-8(14)-EN-13-ONE AND METHYL-(+)-13-OXO-PODOCARP-8(14)-EN-18-OATE FROM ABIETIC ACID
Abad, Antonio,Arno, Manuel,Domingo, Luis R.,Zaragoza, Ramon J.
, p. 4937 - 4940 (2007/10/02)
An efficient method for the preparation of (+)-podocarp-8(14)-en-13-one 6 and methyl-(+)-13-oxo-podocarp-8(14)-en-18-oate 8 from abietic acid is described.
