Benzyl(dimethyl)oxo-lambda~5~-phosphane

Base Information

• Chemical Name: Benzyl(dimethyl)oxo-lambda~5~-phosphane
• CAS No.: 18629-11-3
• Molecular Formula: C9H13OP
• Molecular Weight: 168.175
• DSSTox Substance ID: DTXSID40539309
• Wikidata: Q82415030
• Mol file: 18629-11-3.mol

Synonyms:18629-11-3;[(DIMETHYLPHOSPHORYL)METHYL]BENZENE;Benzyl(dimethyl)oxo-lambda~5~-phosphane;SCHEMBL9972116;DTXSID40539309;G46788;EN300-27146597

Chemical Property of Benzyl(dimethyl)oxo-lambda~5~-phosphane

Chemical Property:

• XLogP3: 0.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 168.070402032
• Heavy Atom Count: 11
• Complexity: 153

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CP(=O)(C)CC1=CC=CC=C1

Technology Process of Benzyl(dimethyl)oxo-lambda~5~-phosphane

There total 6 articles about Benzyl(dimethyl)oxo-lambda~5~-phosphane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

Amino-benzyl-dimethylphosphoniumchlorid → benzyldimethylphosphine oxide (18629-11-3)

Guidance literature:

With water; at 20 ℃; for 2h;

DOI:10.1007/BF00798274

Reference yield: 86.2%

benzyl bromide (100-39-0) + dimethyl phosphine oxide (7211-39-4) → benzyldimethylphosphine oxide (18629-11-3)

Guidance literature:

dimethyl phosphine oxide; With sodium hexamethyldisilazane; In tetrahydrofuran; at 22 ℃; for 0.25h; Inert atmosphere;

benzyl bromide; In tetrahydrofuran; at 0 ℃; for 2h; chemoselective reaction; Inert atmosphere;

DOI:10.1021/acs.organomet.7b00304

Reference yield: 80.0%

benzyl chloride (100-44-7) + dimethyl phosphine oxide (7211-39-4) → benzyldimethylphosphine oxide (18629-11-3)

Guidance literature:

dimethyl phosphine oxide; With sodium hexamethyldisilazane; In tetrahydrofuran; at 22 ℃; for 0.25h; Inert atmosphere;

benzyl chloride; In tetrahydrofuran; at 0 ℃; for 2h; chemoselective reaction; Inert atmosphere;

DOI:10.1021/acs.organomet.7b00304

upstream raw materials:

benzyl chloride

chlorodimethylphosphine

benzophenone

Benzyldimethylphosphinimid

Refernces

• 1、 Wannagat, Ulrich,Muenstedt, Rainer. "UEBER EINIGE REAKTIONEN DER DIALKYLBENZYLPHOSPHINIMIDE". . p. 233 - 238. Retrieved 2007/10/02.