4'-Chloro-5-fluoro-1,1'-biphenyl-2-amine

Base Information

Chemical Name:4'-Chloro-5-fluoro-1,1'-biphenyl-2-amine
CAS No.:188731-34-2
Molecular Formula:C12H9ClFN
Molecular Weight:221.662
Hs Code.:2921490090
Mol file:188731-34-2.mol

Synonyms:4'-chloro-5-fluorobiphenyl-2-amine;4-Chloro-5-fluoro-2-pyridinecarbaldehyde;4-CHLORO-5-FLUOROPICOLINALDEHYDE;4-CHLORO-5-FLUORO-PYRIDINE-2-CARBALDEHYDE;

Suppliers and Price of 4'-Chloro-5-fluoro-1,1'-biphenyl-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Amino-4''-chloro-5-fluorobiphenyl
100mg
$ 65.00

SynQuest Laboratories
2-Amino-4'-chloro-5-fluorobiphenyl
1 g
$ 288.00

Matrix Scientific
4'-Chloro-5-fluoro-1,1'-biphenyl-2-amine 97%
1g
$ 414.00

Crysdot
4'-Chloro-5-fluoro-[1,1'-biphenyl]-2-amine 95+%
5g
$ 769.00

Atlantic Research Chemicals
4''-Chloro-5-fluoro-1,1''-biphenyl-2-amine 95%
1gm:
$ 159.06

AK Scientific
4'-Chloro-5-fluoro-1,1'-biphenyl-2-amine
100mg
$ 306.00

Total 5 raw suppliers

Chemical Property of 4'-Chloro-5-fluoro-1,1'-biphenyl-2-amine

Chemical Property:

PSA：26.02000
LogP:4.30950

Purity/Quality:

99%, ^*data from raw suppliers

2-Amino-4''-chloro-5-fluorobiphenyl ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4'-Chloro-5-fluoro-1,1'-biphenyl-2-amine

There total 13 articles about 4'-Chloro-5-fluoro-1,1'-biphenyl-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 62-53-3
aniline

: 371-40-4
4-fluoroaniline

: 188731-34-2
4’-chloro-5-fluorobiphenyl-2-amine

Guidance literature:: aniline; With hydrogenchloride; sodium nitrite; In water; at 0 ℃; for 0.583333h;

With sodium hydroxide; In water; at 80 ℃;

4-fluoroaniline; regioselective reaction;
DOI:10.1021/acs.joc.6b01840

Reference yield: 68.0%

: 110213-25-7,133611-12-8,77887-33-3
C₆H₄ClN₂O^(1-)*Na⁽¹⁺⁾

: 371-40-4
4-fluoroaniline

: 188731-34-2
4’-chloro-5-fluorobiphenyl-2-amine

Guidance literature:: at 75 ℃; regioselective reaction;
DOI:10.1002/chem.201200430 DOI:10.1002/chem.201200430

Reference yield: 55.0%

: 4-chlorophenylhydrazine hydrochloric acid salt

: 371-40-4
4-fluoroaniline

: 188731-34-2
4’-chloro-5-fluorobiphenyl-2-amine

Guidance literature:: With oxygen; sodium hydroxide; In water; for 24h; Reagent/catalyst; regioselective reaction;
DOI:10.1021/acs.joc.6b01840