Technology Process of Benzeneacetonitrile, 2,3-dichloro-a-(1,2,2-triethoxyethylidene)-
There total 1 articles about Benzeneacetonitrile, 2,3-dichloro-a-(1,2,2-triethoxyethylidene)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2,3-dichlorophenylacetonitrile; Ethyl diethoxyacetate;
With
potassium tert-butylate;
In
1,2-dimethoxyethane;
ethyl iodide;
DOI:10.1021/op4001753
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium ethanolate / ethanol
2.1: hydrogenchloride / 90 °C
3.1: sodium tetrahydroborate / ethanol / 25 °C
4.1: diethylamino-sulfur trifluoride / -78 - -10 °C
5.1: industrial methylated spirits / ethanol; water; dimethyl sulfoxide / 16 h / 65 °C
6.1: triethylamine / water; dimethyl sulfoxide / 0.25 h / 80 °C
6.2: 0.5 h
With
hydrogenchloride; sodium tetrahydroborate; diethylamino-sulfur trifluoride; sodium ethanolate; triethylamine;
In
ethanol; water; dimethyl sulfoxide;
DOI:10.1021/op4001753
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium ethanolate / ethanol
2: hydrogenchloride / 90 °C
3: sodium tetrahydroborate / ethanol / 25 °C
4: diethylamino-sulfur trifluoride / -78 - -10 °C
With
hydrogenchloride; sodium tetrahydroborate; diethylamino-sulfur trifluoride; sodium ethanolate;
In
ethanol;
DOI:10.1021/op4001753
