(2S)-1-(2,3-Diaminophenoxy)-3-(dibenzylamino)propan-2-ol

Base Information

Chemical Name:(2S)-1-(2,3-Diaminophenoxy)-3-(dibenzylamino)propan-2-ol
CAS No.:189119-14-0
Molecular Formula:C23H27N3O2
Molecular Weight:377.486
Hs Code.:
DSSTox Substance ID:DTXSID90710121
Wikidata:Q82645364

Synonyms:189119-14-0;(2S)-1-(2,3-Diaminophenoxy)-3-(dibenzylamino)propan-2-ol;SCHEMBL7961071;DTXSID90710121;RDRQEVMSENHBRM-FQEVSTJZSA-N;(S)-[3-(N,N-Dibenzylamino)-2-hydroxypropoxy]-2,3-diamino benzene;(S)-[3-(N,N-Dibenzylamino)-2-hydroxypropoxy]-2,3-diaminobenzene;(S) - [3 - (N, N-Dibenzylamino)-2-hydroxypropoxy]-2,3-diamino benzene

Suppliers and Price of (2S)-1-(2,3-Diaminophenoxy)-3-(dibenzylamino)propan-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of (2S)-1-(2,3-Diaminophenoxy)-3-(dibenzylamino)propan-2-ol

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:377.21032711
Heavy Atom Count:28
Complexity:404

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CN(CC2=CC=CC=C2)CC(COC3=CC=CC(=C3N)N)O
Isomeric SMILES:C1=CC=C(C=C1)CN(CC2=CC=CC=C2)C[C@@H](COC3=CC=CC(=C3N)N)O

Technology Process of (2S)-1-(2,3-Diaminophenoxy)-3-(dibenzylamino)propan-2-ol

There total 3 articles about (2S)-1-(2,3-Diaminophenoxy)-3-(dibenzylamino)propan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 189119-13-9
(S)-[3-(N,N-Dibenzylamino)-2-hydroxypropoxy]-2-amino-3-nitrobenzene

: 189119-14-0
(S)-[3-(N,N-Dibenzylamino)-2-hydroxypropoxy]-2,3-diamino benzene

Guidance literature:: With sodium dithionite; sodium hydrogencarbonate; In ethanol; water; at 20 ℃; for 16h;
DOI:10.1016/j.bmcl.2006.08.010

Reference yield:

: 603-85-0
2-Amino-3-nitrophenol

: 189119-14-0
(S)-[3-(N,N-Dibenzylamino)-2-hydroxypropoxy]-2,3-diamino benzene

Guidance literature:: Multi-step reaction with 3 steps

1: 99 percent / K₂CO₃ / acetone / 18 h / Heating

2: 78 percent / methanol / 10 h / Heating

3: 81 percent / Na₂S₂O₄; NaHCO₃ / ethanol; H₂O / 16 h / 20 °C

With sodium dithionite; sodium hydrogencarbonate; potassium carbonate; In methanol; ethanol; water; acetone;
DOI:10.1016/j.bmcl.2006.08.010

Reference yield:

: 132059-11-1
R-<1-(2-amino-3-nitrophenoxy)>-2',3'-epoxypropane

: 189119-14-0
(S)-[3-(N,N-Dibenzylamino)-2-hydroxypropoxy]-2,3-diamino benzene

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / methanol / 10 h / Heating

2: 81 percent / Na₂S₂O₄; NaHCO₃ / ethanol; H₂O / 16 h / 20 °C

With sodium dithionite; sodium hydrogencarbonate; In methanol; ethanol; water;
DOI:10.1016/j.bmcl.2006.08.010