2-Ethoxy-1,3-dimethoxy-5-nitrobenzene

Base Information

Chemical Name:2-Ethoxy-1,3-dimethoxy-5-nitrobenzene
CAS No.:189564-60-1
Molecular Formula:C10H13NO5
Molecular Weight:227.217
Hs Code.:
DSSTox Substance ID:DTXSID20596470
Wikidata:Q82491732

Synonyms:2-Ethoxy-1,3-dimethoxy-5-nitrobenzene;189564-60-1;Benzene, 2-ethoxy-1,3-dimethoxy-5-nitro-;SCHEMBL7513156;DTXSID20596470;SY311820

Suppliers and Price of 2-Ethoxy-1,3-dimethoxy-5-nitrobenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-Ethoxy-1,3-dimethoxy-5-nitrobenzene

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:227.07937252
Heavy Atom Count:16
Complexity:216

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=C(C=C(C=C1OC)[N+](=O)[O-])OC

Technology Process of 2-Ethoxy-1,3-dimethoxy-5-nitrobenzene

There total 2 articles about 2-Ethoxy-1,3-dimethoxy-5-nitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 64-17-5
ethanol

: 6307-90-0
3,4,5-trimethoxy-1-nitrobenzene

: 189564-60-1
3,5-dimethoxy-4-ethoxynitrobenzene

Guidance literature:: ethanol; With sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; for 0.666667h;

3,4,5-trimethoxy-1-nitrobenzene; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; for 0.25h;
DOI:10.1016/S0960-894X(00)00493-5

Reference yield:

: 189564-60-1
3,5-dimethoxy-4-ethoxynitrobenzene

Guidance literature:

Reference yield:

: 189564-60-1
3,5-dimethoxy-4-ethoxynitrobenzene

: (6,7-dimethoxy-quinazolin-4-yl)-(4-ethoxy-3,5-dimethoxy-phenyl)-amine

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Pd/C

2: pyridine*HCl / 2-ethoxy-ethanol

With hydrogen; pyridine hydrochloride; palladium on activated charcoal; In 2-ethoxy-ethanol; 1: Catalytic hydrogenation / 2: Substitution;
DOI:10.1016/S0960-894X(00)00493-5