1-(2-Chloroethyl)-2-methylpiperidine

Base Information

Chemical Name:1-(2-Chloroethyl)-2-methylpiperidine
CAS No.:53324-72-4
Molecular Formula:C8H16 Cl N
Molecular Weight:161.675
Hs Code.:2933399090
European Community (EC) Number:258-477-8
DSSTox Substance ID:DTXSID30967930
Nikkaji Number:J295.931C
Mol file:53324-72-4.mol

Synonyms:1-(2-Chloroethyl)-2-methylpiperidine;53324-72-4;EINECS 258-477-8;SCHEMBL11470180;DTXSID30967930;AKOS010541214

Suppliers and Price of 1-(2-Chloroethyl)-2-methylpiperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
1-(2-chloroethyl)-2-methyl-Piperidine 97.00%
25G
$ 4010.00

AccelPharmtech
1-(2-chloroethyl)-2-methyl-Piperidine 97.00%
5G
$ 2180.00

AccelPharmtech
1-(2-chloroethyl)-2-methyl-Piperidine 97.00%
1G
$ 1940.00

Total 3 raw suppliers

Chemical Property of 1-(2-Chloroethyl)-2-methylpiperidine

Chemical Property:

Vapor Pressure:0.279mmHg at 25°C
Boiling Point:203.3°Cat760mmHg
PKA:8.63±0.10(Predicted)
Flash Point:76.8°C
PSA：3.24000
Density:0.971g/cm³
LogP:2.03750
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:161.0971272
Heavy Atom Count:10
Complexity:95.3

Purity/Quality:

99% ^*data from raw suppliers

1-(2-chloroethyl)-2-methyl-Piperidine 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCCCN1CCCl

Technology Process of 1-(2-Chloroethyl)-2-methylpiperidine

There total 4 articles about 1-(2-Chloroethyl)-2-methylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67-66-3,8013-54-5
chloroform

: 53324-72-4
(+/-)-N-(2-Chloroethyl)-2-methylpiperidine

Guidance literature:: With thionyl chloride;
DOI:10.1021/ja01178a028

Reference yield:

: 17719-74-3
1-(2-hydroxyethyl)-2-methylpiperidine

: 53324-72-4
(+/-)-N-(2-Chloroethyl)-2-methylpiperidine

Guidance literature:: With dmap; thionyl chloride; In chloroform; for 2h; Ambient temperature;
DOI:10.1002/ardp.19953280705

Reference yield:

: 109-05-7,3000-79-1
2-Methylpiperidin

: 53324-72-4
(+/-)-N-(2-Chloroethyl)-2-methylpiperidine

Guidance literature:: Multi-step reaction with 2 steps

1: KOH / acetonitrile / Ambient temperature

2: SOCl₂, 4-DMAP / CHCl₃ / 2 h / Ambient temperature

With dmap; potassium hydroxide; thionyl chloride; In chloroform; acetonitrile;
DOI:10.1002/ardp.19953280705