Phosphinothioic acid, methylphenyl-

Base Information

• Chemical Name: Phosphinothioic acid, methylphenyl-
• CAS No.: 18962-89-5
• Molecular Formula: C7H9OPS
• Molecular Weight: 172.188
• Mol file: 18962-89-5.mol

Synonyms:

Chemical Property of Phosphinothioic acid, methylphenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phosphinothioic acid, methylphenyl-

There total 10 articles about Phosphinothioic acid, methylphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

n-butyl methyl-phenylphosphinate (51103-74-3) → methylphenylphosphinothioic acid (18962-89-5)

Guidance literature:

n-butyl methyl-phenylphosphinate; With aniline; lithium hexamethyldisilazane; In tetrahydrofuran; toluene; at 0 - 20 ℃; for 2h; Inert atmosphere;

With carbon disulfide; In tetrahydrofuran; toluene; at 20 ℃; Inert atmosphere;

DOI:10.1021/acs.joc.0c01151

Reference yield: 85.0%

methyl-N,P-diphenylphosphinic amide (51703-89-0) → methylphenylphosphinothioic acid (18962-89-5)

Guidance literature:

methyl-N,P-diphenylphosphinic amide; With lithium hexamethyldisilazane; In tetrahydrofuran; toluene; at 0 - 20 ℃; for 1h; Inert atmosphere;

With carbon disulfide; In tetrahydrofuran; toluene; at 20 ℃; Reagent/catalyst; Temperature; Solvent; Inert atmosphere;

DOI:10.1021/acs.joc.0c01151

Reference yield: 9.0%

butyl phenylphosphinate (6172-81-2) + methyllithium (917-54-4) → methylphenylphosphinothioic acid (18962-89-5)

Guidance literature:

butyl phenylphosphinate; methyllithium; In tetrahydrofuran; diethyl ether; at -78 - 20 ℃; for 3h; Inert atmosphere;

With sulfur; In tetrahydrofuran; diethyl ether; at 20 ℃; Inert atmosphere;

DOI:10.1021/acs.joc.0c01151

upstream raw materials:

n-butyl methyl-phenylphosphinate

methylphenylphosphinic acid

methyl-N,P-diphenylphosphinic amide

butyl phenylphosphinate