51103-74-3

Upstream product

• 5761-97-7 methyl(phenyl)phosphinic chloride 
• 71-36-3 butan-1-ol 
• 108-86-1 bromobenzene 
• 6172-80-1 butyl methylphosphinate 
• 1779-48-2 phenylphosphinic acid 
• 4271-13-0 methylphenylphosphinic acid 
• 109-65-9 1-bromo-butane 
• 941-69-5 N-phenyl-maleimide 
• 109891-15-8 5-methyl-4-chloro-1-phenyl-1,2-dihydrophosphinine 1-oxide 
• 109891-12-5 3-methyl-4-chloro-1,2-dihydro-1-phenylphosphorin 1-oxide 

Downstream Products

• 18962-89-5 methylphenylphosphinothioic acid 

Relevant academic research and scientific papers

Synthesis of n-butyl ester and n-butylamide of methyl-phenylphosphinic acid: Two case studies

n-Butyl methyl-phenylphosphinate and methyl-phenylphosphinic n-butylamide were synthesized by different methods: the reaction of methyl-phenylphosphinic chloride withnBuOH ornBuNH2, respectively, the T3P-promoted derivatiz

Evaluation and development of methodologies for the synthesis of thiophosphinic acids

Thiophosphorus acids R1R2P(S)OH constitute an important class of organophosphorus compounds, in which the phosphorus atom is intrinsically chiral if R1 ≠ R2. In connection with a project aimed at the preparation of chiral thiophosphorus acids, various available literature methods were considered, but few fit the requirement of odorless reagents. Herein, the results of our studies on the synthesis of thiophosphinic acids are reported. Ultimately, two major approaches were selected: (1) the Stec reaction of phosphorus amides with carbon disulfide; and (2) the one-pot synthesis of thiophosphorus acids from H-phosphinates, an organometallic nucleophile, and quenching with elemental sulfur. An application to the preparation of a potential chiral phosphorus organocatalyst is also reported.

Synthesis and use of 6-, 7-and 8-membered P-heterocycles

The synthesis of new families of P-heterocycles by reductive modifications, ring enlargement and Diels-Alder cycloaddition is described.

Photolysis of the cycloadduct of a 1,2-dihydrophosphinine oxide with N-phenylmaleimide in the presence of protic species: New aspects on the mechanism of the fragmentation of a 2-phosphabicyclo[2.2.2]octene

Phosphabicyclo[2.2.2]octene 2 is useful in the UV light mediated phosphorylation of protic species. Experiments suggest that the fragmentation takes place according to concurrent EA and AE mechanisms.