N-(4-bromo-2-cyanophenyl)benzamide

Base Information

Chemical Name:N-(4-bromo-2-cyanophenyl)benzamide
CAS No.:189635-01-6
Molecular Formula:C14H9BrN2O
Molecular Weight:301.14
Hs Code.:
DSSTox Substance ID:DTXSID201296353
Mol file:189635-01-6.mol

Synonyms:N-(4-bromo-2-cyanophenyl)benzamide;189635-01-6;SCHEMBL9454022;DTXSID201296353;AKOS017559659

Suppliers and Price of N-(4-bromo-2-cyanophenyl)benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-(4-BROMO-2-CYANOPHENYL)BENZAMIDE 95.00%
5MG
$ 496.44

Total 3 raw suppliers

Chemical Property of N-(4-bromo-2-cyanophenyl)benzamide

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:299.98983
Heavy Atom Count:18
Complexity:343

Purity/Quality:

98% ^*data from raw suppliers

N-(4-BROMO-2-CYANOPHENYL)BENZAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)NC2=C(C=C(C=C2)Br)C#N

Technology Process of N-(4-bromo-2-cyanophenyl)benzamide

There total 8 articles about N-(4-bromo-2-cyanophenyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 589-21-9
(4-bromophenyl)hydrazine

: 189635-01-6
N-(4-bromo-2-cyanophenyl)benzamide

Guidance literature:: Multi-step reaction with 4 steps

1: acetic acid / ethanol / 100 °C / Inert atmosphere

2: polyphosphoric acid / 120 °C / Inert atmosphere

3: tert.-butylnitrite / acetonitrile / 2 h / 80 °C / Sealed tube; Inert atmosphere

4: iron(III) trifluoromethanesulfonate / acetonitrile / 14 h / 120 °C / Sealed tube; Inert atmosphere

With tert.-butylnitrite; iron(III) trifluoromethanesulfonate; acetic acid; In ethanol; acetonitrile;
DOI:10.1021/acs.orglett.8b01294

Reference yield:

: 35082-17-8
1-(4-bromophenyl)-2-(1-phenylethylidene)hydrazine

: 189635-01-6
N-(4-bromo-2-cyanophenyl)benzamide

Guidance literature:: Multi-step reaction with 3 steps

1: polyphosphoric acid / 120 °C / Inert atmosphere

2: tert.-butylnitrite / acetonitrile / 2 h / 80 °C / Sealed tube; Inert atmosphere

3: iron(III) trifluoromethanesulfonate / acetonitrile / 14 h / 120 °C / Sealed tube; Inert atmosphere

With tert.-butylnitrite; iron(III) trifluoromethanesulfonate; In acetonitrile;
DOI:10.1021/acs.orglett.8b01294

Reference yield:

: 83515-06-4
5-bromo-2-phenylindole

: 189635-01-6
N-(4-bromo-2-cyanophenyl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: tert.-butylnitrite / acetonitrile / 2 h / 80 °C / Sealed tube; Inert atmosphere

2: iron(III) trifluoromethanesulfonate / acetonitrile / 14 h / 120 °C / Sealed tube; Inert atmosphere

With tert.-butylnitrite; iron(III) trifluoromethanesulfonate; In acetonitrile;
DOI:10.1021/acs.orglett.8b01294