Phenol, 2-ethenyl-6-methoxy- (9CI)

Base Information

• Chemical Name: Phenol, 2-ethenyl-6-methoxy- (9CI)
• CAS No.: 120550-69-8
• Molecular Formula: C9H10 O2
• Molecular Weight: 150.177
• Mol file: 120550-69-8.mol

Synonyms:Phenol, 2-ethenyl-6-methoxy- (9CI)

Chemical Property of Phenol, 2-ethenyl-6-methoxy- (9CI)

Chemical Property:

• Vapor Pressure: 0.0172mmHg at 25°C
• Boiling Point: 246.6°C at 760 mmHg
• Flash Point: 113.4°C
• PSA: 29.46000
• Density: 1.089g/cm³
• LogP: 2.04380

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phenol, 2-ethenyl-6-methoxy- (9CI)

There total 2 articles about Phenol, 2-ethenyl-6-methoxy- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

Methyltriphenylphosphonium bromide (1779-49-3) + 3-methoxy-2-hydroxybenzaldehyde (148-53-8) → 2-hydroxy-3-methoxystyrene (120550-69-8)

Guidance literature:

With Amberlite IR-400; In N,N-dimethyl-formamide; at 95 ℃; for 10h; Inert atmosphere;

DOI:10.1080/00397911.2016.1276191

Reference yield:

(trimethylsilyl)methylmagnesium chloride (13170-43-9) + 3-methoxy-2-hydroxybenzaldehyde (148-53-8) → 2-hydroxy-3-methoxystyrene (120550-69-8)

Guidance literature:

With thionyl chloride; Multistep reaction; 1.) ether;

DOI:10.3891/acta.chem.scand.43-0044

Reference yield: 97.0%

mesitylenecarbonitrile oxide (2904-57-6) + 2-hydroxy-3-methoxystyrene (120550-69-8) → 5-(2-hydroxy-3-methoxy)phenyl-3-(2,4,6-trimethyl)phenyl-2-isoxazoline

Guidance literature:

With 1-(3,5-bis(trifluoromethyl)phenyl)-3-((S)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)urea; In toluene; at 0 ℃; for 12h; enantioselective reaction; Inert atmosphere;

DOI:10.1002/anie.201705662

upstream raw materials:

(trimethylsilyl)methylmagnesium chloride

3-methoxy-2-hydroxybenzaldehyde

Methyltriphenylphosphonium bromide

Downstream raw materials:

methyl 2-(2-methoxy-6-vinylphenoxy)-6-methylbenzoate

2-(2-methoxy-6-vinylphenoxy)-6-methylbenzoic acid

(7S,8R,9E)-14-methoxy-8-(4-methoxyphenoxy)-4-methyl-7-pentyl-7,8-dihydro-5H-dibenzo[b,j]dioxacycloundecin-5-one

2-(2-Methoxy-6-vinylphenoxy)-3-butenyl 4-methylbenzenesulfonate

Refernces

• 1、 Valkute, Tushar R.,Aratikatla, Eswar K.,Bhattacharya, Asish K.. "Efficient synthesis of functionalized olefins by Wittig reaction using Amberlite resin as a mild base". . p. 581 - 589. Retrieved 2017/03/15.
• 2、 Parasram, Marvin,Iaroshenko, Viktor O.,Gevorgyan, Vladimir. "Endo-selective pd-catalyzed silyl methyl heck reaction". supporting information. p. 17926 - 17929. Retrieved 2015/03/04.