1,2-Bis(4-hydroxyphenoxy)ethane

Base Information

• Chemical Name: 1,2-Bis(4-hydroxyphenoxy)ethane
• CAS No.: 24209-90-3
• Molecular Formula: C14H14 O4
• Molecular Weight: 246.263
• Hs Code.: 2909500000
• NSC Number: 62372
• DSSTox Substance ID: DTXSID50289606
• Nikkaji Number: J1.710.445D
• Wikidata: Q82026978
• Mol file: 24209-90-3.mol

Synonyms:1,2-bis(4-hydroxyphenoxy)ethane;4-[2-(4-hydroxyphenoxy)ethoxy]phenol;24209-90-3;NSC62372;NCIOpen2_002563;SCHEMBL226548;DTXSID50289606;NSC-62372

Chemical Property of 1,2-Bis(4-hydroxyphenoxy)ethane

Chemical Property:

• Vapor Pressure: 2.5E-09mmHg at 25°C
• Boiling Point: 466.6°Cat760mmHg
• Flash Point: 236°C
• PSA: 58.92000
• Density: 1.261g/cm³
• LogP: 2.55560
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 246.08920892
• Heavy Atom Count: 18
• Complexity: 194

Purity/Quality:

99% ^*data from raw suppliers

1,2-BIS(4-HYDROXYPHENOXY)ETHANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1O)OCCOC2=CC=C(C=C2)O

Technology Process of 1,2-Bis(4-hydroxyphenoxy)ethane

There total 2 articles about 1,2-Bis(4-hydroxyphenoxy)ethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

ethylene dibromide (106-93-4) + hydroquinone (123-31-9,8027-02-9) → 4,4'-dihydroxy-1,2-diphenoxyethane (24209-90-3)

Guidance literature:

hydroquinone; With potassium carbonate; In acetonitrile; at 85 ℃; Inert atmosphere;

ethylene dibromide; In acetonitrile; for 12h; Inert atmosphere;

DOI:10.1080/10610278.2018.1539228

Reference yield:

→ 4,4'-dihydroxy-1,2-diphenoxyethane (24209-90-3)

Guidance literature:

hydroquinone (1a), ethylene chloride, KOH, in DMSO, under N2;

Reference yield: 87.0%

1,3-propanesultone (1120-71-4) + 4,4'-dihydroxy-1,2-diphenoxyethane (24209-90-3) → C20H24O10S2(2-)*2Na(1+)

Guidance literature:

With sodium hydroxide; In 1,4-dioxane; water; at 20 ℃; for 12h;

DOI:10.1080/10610278.2018.1539228

upstream raw materials:

ethylene dibromide

hydroquinone

Downstream raw materials:

1,2-bis-(4-methoxy-phenoxy)-ethane

Refernces