Benzoic acid,4-chloro-, 2-(4-chlorobenzoyl)hydrazide

Base Information

• Chemical Name: Benzoic acid,4-chloro-, 2-(4-chlorobenzoyl)hydrazide
• CAS No.: 895-84-1
• Molecular Formula: C14H10 Cl2 N2 O2
• Molecular Weight: 309.152
• Mol file: 895-84-1.mol

Synonyms:Hydrazine,1,2-bis(p-chlorobenzoyl)- (7CI,8CI); 1,2-Bis(4-chlorobenzoyl)hydrazine;N,N'-Bis(p-chlorobenzoyl)hydrazine; NSC 60385

Chemical Property of Benzoic acid,4-chloro-, 2-(4-chlorobenzoyl)hydrazide

Chemical Property:

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoic acid,4-chloro-, 2-(4-chlorobenzoyl)hydrazide

There total 12 articles about Benzoic acid,4-chloro-, 2-(4-chlorobenzoyl)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-chlorobenzoic acid hydrazide (536-40-3) → N,N'-bis(p-chlorobenzoyl)hydrazine (895-84-1)

Guidance literature:

With copper diacetate; for 0.0833333h; microwave irradiation;

DOI:10.1081/SCC-120025183

Reference yield: 75.0%

4-chloro-benzoyl chloride (122-01-0) + 4-chlorobenzoic acid hydrazide (536-40-3) → N,N'-bis(p-chlorobenzoyl)hydrazine (895-84-1)

Guidance literature:

With pyridine; for 36h; Reflux;

DOI:10.1016/j.bioorg.2018.09.036

Reference yield: 64.84%

C15H12Cl2N4O3 (202273-29-8) → N,N'-bis(p-chlorobenzoyl)hydrazine (895-84-1)

Guidance literature:

With aluminium trichloride; at 170 - 180 ℃; for 3h;

upstream raw materials:

carbon disulfide

1,2-di-(p-chlorobenzoyl)diazene

4-chloro-benzoyl chloride

thiosemicarbazide

Downstream raw materials:

2,5-bis(p-chlorophenyl)-1,3,4-thiadiazole

N-acetonyl-4-chlorobenzamide

4-chloro-benzoic acid-[N'-(4-chloro-benzyl)-hydrazide]

1,2-di-(p-chlorobenzoyl)diazene

Refernces

• 1、 Sakurai, Masayoshi,Kihara, Nobuhiro,Watanabe, Nobuhiro,Ikari, Yoshihiro,Takata, Toshikazu. "Synthesis of α-aminocarbonyl compounds via hetero dielsalder reaction". supporting information. p. 144 - 147. Retrieved 2018/01/01.
• 2、 More, Priyanka Anant,Gadilohar, Balu Laxman,Shankarling, Ganapati Subray. "In situ generated cetyltrimethylammonium bisulphate in choline chloride-urea deep eutectic solvent: A novel catalytic system for one pot synthesis of 1,3,4-oxadiazole". . p. 1393 - 1398. Retrieved 2014/08/18.