Technology Process of Moracin C
There total 41 articles about Moracin C which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
1-methyl-pyrrolidin-2-one; sodium hydroxide; 1-dodecylthiol;
at 130 ℃;
for 24h;
Inert atmosphere;
DOI:10.3390/molecules26051327
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: 1H-imidazole / tetrahydrofuran / 4 h / 0 - 20 °C
2.1: sodium tetrahydroborate / methanol / 4 h / 20 °C
3.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C
3.2: -78 - 20 °C
3.3: 20 °C / pH 5
4.1: potassium carbonate; palladium diacetate; tricyclohexylphosphine / water; 1,2-dimethoxyethane / 2 h / 80 °C / Inert atmosphere
5.1: 1H-imidazole / tetrahydrofuran / 2 h / 20 °C
6.1: n-butyllithium / hexane; cyclohexane / 0.5 h / Inert atmosphere; Heating
6.2: 2 h / Inert atmosphere; Heating
7.1: n-butyllithium; diphenylphosphane / tetrahydrofuran; hexane / 36 h / Inert atmosphere; Reflux
With
1H-imidazole; sodium tetrahydroborate; n-butyllithium; palladium diacetate; potassium carbonate; diphenylphosphane; tricyclohexylphosphine;
In
tetrahydrofuran; methanol; 1,2-dimethoxyethane; hexane; cyclohexane; water;
DOI:10.1016/j.tetlet.2015.05.093
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 93 percent / imidazole / dimethylformamide / 24 h / Ambient temperature
3: Ph2PLi / tetrahydrofuran; hexane / 16 h / Heating
4: Bu4NF / tetrahydrofuran / Ambient temperature
With
1H-imidazole; tetrabutyl ammonium fluoride; lithium diphenylphosphide;
In
tetrahydrofuran; hexane; N,N-dimethyl-formamide;
