5-(4-(Benzyloxy)phenyl)-2,2-dimethyl-1,3-dioxolan-4-one

Base Information

Chemical Name:5-(4-(Benzyloxy)phenyl)-2,2-dimethyl-1,3-dioxolan-4-one
CAS No.:192573-25-4
Molecular Formula:C18H18O4
Molecular Weight:298.339
Hs Code.:
European Community (EC) Number:655-387-4

Synonyms:5-(4-(Benzyloxy)phenyl)-2,2-dimethyl-1,3-dioxolan-4-one;AKOS024417659

Suppliers and Price of 5-(4-(Benzyloxy)phenyl)-2,2-dimethyl-1,3-dioxolan-4-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(4-(Benzyloxy)phenyl)-2,2-dimethyl-1,3-dioxolan-4-one

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:298.12050905
Heavy Atom Count:22
Complexity:379

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(OC(C(=O)O1)C2=CC=C(C=C2)OCC3=CC=CC=C3)C

Technology Process of 5-(4-(Benzyloxy)phenyl)-2,2-dimethyl-1,3-dioxolan-4-one

There total 2 articles about 5-(4-(Benzyloxy)phenyl)-2,2-dimethyl-1,3-dioxolan-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 100-39-0
benzyl bromide

: 173192-07-9
5-(4-hydroxyphenyl)-2,2-dimethyl-1,3-dioxolan-4-one

: 192573-25-4
5-(4-benzyloxyphenyl)-2,2-dimethyl-1,3-dioxolan-4-one

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; Ambient temperature;
DOI:10.1016/S0040-4020(97)00456-0

Reference yield:

: 1198-84-1
4-hydroxymandelic acid

: 192573-25-4
5-(4-benzyloxyphenyl)-2,2-dimethyl-1,3-dioxolan-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 67 percent / BF₃*OEt₂

2: 93 percent / K₂CO₃ / dimethylformamide / Ambient temperature

With boron trifluoride diethyl etherate; potassium carbonate; In N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(97)00456-0

Reference yield:

: 192573-25-4
5-(4-benzyloxyphenyl)-2,2-dimethyl-1,3-dioxolan-4-one

: (S)-(4-benzyloxy-phenyl)-hydroxy-acetic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 57 percent / Ti(OiPr)4, (4R,5R)-α,α,α',α'-tetraphenyl-2,2-dimethyl-1,3-dioxolane-4,5-dimethanol / tetrahydrofuran / 72 h / Ambient temperature

2: 27 percent / AcCl / tetrahydrofuran / Ambient temperature

With titanium(IV) isopropylate; (R,R)-TADDOL; acetyl chloride; In tetrahydrofuran;
DOI:10.1016/S0040-4020(97)00456-0