ethyl N-[6-amino-4-[[(2Z)-2-hydroxyimino-3-(4-methoxy-N-methylanilino)propyl]amino]-5-nitropyridin-2-yl]carbamate

Base Information

Chemical Name:ethyl N-[6-amino-4-[[(2Z)-2-hydroxyimino-3-(4-methoxy-N-methylanilino)propyl]amino]-5-nitropyridin-2-yl]carbamate
CAS No.:82585-58-8
Molecular Formula:C19H25 N7 O6
Molecular Weight:447.451
Hs Code.:
NSC Number:266525
DSSTox Substance ID:DTXSID10421060

Synonyms:NSC266525;82585-58-8;DTXSID10421060;NSC-266525

Suppliers and Price of ethyl N-[6-amino-4-[[(2Z)-2-hydroxyimino-3-(4-methoxy-N-methylanilino)propyl]amino]-5-nitropyridin-2-yl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of ethyl N-[6-amino-4-[[(2Z)-2-hydroxyimino-3-(4-methoxy-N-methylanilino)propyl]amino]-5-nitropyridin-2-yl]carbamate

Chemical Property:

Vapor Pressure:5.71E-20mmHg at 25°C
Boiling Point:689.7°Cat760mmHg
Flash Point:370.9°C
Density:1.4g/cm³
XLogP3:3.5
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:10
Exact Mass:447.18663154
Heavy Atom Count:32
Complexity:638

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)NC1=NC(=C(C(=C1)NCC(=NO)CN(C)C2=CC=C(C=C2)OC)[N+](=O)[O-])N
Isomeric SMILES:CCOC(=O)NC1=NC(=C(C(=C1)NC/C(=N/O)/CN(C)C2=CC=C(C=C2)OC)[N+](=O)[O-])N

Technology Process of ethyl N-[6-amino-4-[[(2Z)-2-hydroxyimino-3-(4-methoxy-N-methylanilino)propyl]amino]-5-nitropyridin-2-yl]carbamate

There total 2 articles about ethyl N-[6-amino-4-[[(2Z)-2-hydroxyimino-3-(4-methoxy-N-methylanilino)propyl]amino]-5-nitropyridin-2-yl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 6506-86-1
ethyl (6-amino-4-chloro-5-nitropyridin-2-yl)carbamate

: 82740-35-0
1-Amino-3-[(4-methoxy-phenyl)-methyl-amino]-propan-2-one oxime

: 82585-58-8
(6-Amino-4-{2-[(E)-hydroxyimino]-3-[(4-methoxy-phenyl)-methyl-amino]-propylamino}-5-nitro-pyridin-2-yl)-carbamic acid ethyl ester

Guidance literature:: With triethylamine; In methanol; at 75 ℃; for 15h;
DOI:10.1021/jm00351a008

Reference yield:

: 82585-46-4
2-{2-[(E)-Hydroxyimino]-3-[(4-methoxy-phenyl)-methyl-amino]-propyl}-isoindole-1,3-dione

: 82585-58-8
(6-Amino-4-{2-[(E)-hydroxyimino]-3-[(4-methoxy-phenyl)-methyl-amino]-propylamino}-5-nitro-pyridin-2-yl)-carbamic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine / ethanol / 22 h / 40 °C

2: 75 percent / Et₃N / methanol / 15 h / 75 °C

With triethylamine; hydrazine; In methanol; ethanol;
DOI:10.1021/jm00351a008