tert-Butyl (5-bromo-2-chloropyridin-3-yl)carbamate

Base Information

Chemical Name:tert-Butyl (5-bromo-2-chloropyridin-3-yl)carbamate
CAS No.:193888-15-2
Molecular Formula:C10H12BrClN2O2
Molecular Weight:307.57100
Hs Code.:2933399090
DSSTox Substance ID:DTXSID70446597
Wikidata:Q82265305
Mol file:193888-15-2.mol

Synonyms:193888-15-2;tert-Butyl (5-bromo-2-chloropyridin-3-yl)carbamate;3-(BOC-Amino)-5-bromo-2-chloropyridine;tert-butyl N-(5-bromo-2-chloropyridin-3-yl)carbamate;tert-Butyl(5-bromo-2-chloropyridin-3-yl)carbamate;SCHEMBL380261;DTXSID70446597;MFCD19237226;AKOS015892192;BS-25033;CS-0371710;FT-0727065;F74788;EN300-3245948;A880234

Suppliers and Price of tert-Butyl (5-bromo-2-chloropyridin-3-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
tert-Butyl(5-Bromo-2-chloropyridin-3-yl)carbamate
100mg
$ 60.00

Crysdot
tert-Butyl(5-bromo-2-chloropyridin-3-yl)carbamate 95+%
25g
$ 468.00

Chemenu
tert-Butyl(5-bromo-2-chloropyridin-3-yl)carbamate 95%
25g
$ 438.00

Chemcia Scientific
(5-Bromo-2-chloro-pyridin-3-yl)-carbamicacidtert-butylester ＞97%
10 G
$ 195.00

American Custom Chemicals Corporation
TERT-BUTYL-(5-BROMO-2-CHLOROPYRIDIN-3-YL)CARBAMATE 95.00%
5MG
$ 502.71

AK Scientific
3-(BOC-Amino)-5-bromo-2-chloropyridine
10g
$ 317.00

Total 13 raw suppliers

Chemical Property of tert-Butyl (5-bromo-2-chloropyridin-3-yl)carbamate

Chemical Property:

PSA：54.71000
LogP:3.85810
Storage Temp.:2-8°C
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:305.97707
Heavy Atom Count:16
Complexity:258

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl(5-Bromo-2-chloropyridin-3-yl)carbamate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=C(N=CC(=C1)Br)Cl

Technology Process of tert-Butyl (5-bromo-2-chloropyridin-3-yl)carbamate

There total 1 articles about tert-Butyl (5-bromo-2-chloropyridin-3-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 588729-99-1
3-amino-5-bromo-2-chloropyridine

: 24424-99-5
di-tert-butyl dicarbonate

: 193888-15-2
tert-butyl 5-bromo-2-chloropyridin-3-ylcarbamate

Guidance literature:: 3-amino-5-bromo-2-chloropyridine; With sodium hydride; In tetrahydrofuran; mineral oil; for 0.333333h; Cooling with ice;

di-tert-butyl dicarbonate; In tetrahydrofuran; mineral oil; at 60 ℃; Cooling with ice;

Reference yield:

: 34897-85-3
o-azidobenzoyl chloride

: 193888-15-2
tert-butyl 5-bromo-2-chloropyridin-3-ylcarbamate

: C₂₀H₁₇N₃O

Guidance literature:: With pyridine; lithium acetanilide; C₁₁H₁₄NO^(1-)*Li⁽¹⁺⁾; silyl resin; tert.-butyl lithium; potassium hydride; thiophenol; triethylamine; trifluoroacetic acid; tin(ll) chloride; Yield given. Multistep reaction;
DOI:10.1021/jo9710745

Reference yield:

: 947188-09-2
2-Azido-4-methoxy-benzoyl chloride

: 193888-15-2
tert-butyl 5-bromo-2-chloropyridin-3-ylcarbamate

: C₂₆H₂₄F₃N₃O₃

Guidance literature:: With pyridine; lithium acetanilide; C₁₁H₁₄NO^(1-)*Li⁽¹⁺⁾; silyl resin; tert.-butyl lithium; potassium hydride; thiophenol; triethylamine; trifluoroacetic acid; tin(ll) chloride; Yield given. Multistep reaction;
DOI:10.1021/jo9710745