6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin- 9-ol,5,8,13,13a-tetrahydro-10-methoxy-

Base Information

Chemical Name:6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin- 9-ol,5,8,13,13a-tetrahydro-10-methoxy-
CAS No.:17388-17-9
Molecular Formula:C19H19NO4
Molecular Weight:325.364
Hs Code.:

Synonyms:Tetrahydroberberrubine;Nandinine DL-form;Nandinine ,(+/-)-;6H-Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizin-9-ol,5,8,13,13a-tetrahydro-10-methoxy-;(+/-)-Nandinine;(RS)-Nandinine;(+/-)-5,6,13,14-Tetrahydro-9-hydroxy-10-methoxy-2,3-(methylenedioxy)-8H-dibenzo(a,g)quinolizine;Nandinine,DL-;

Suppliers and Price of 6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin- 9-ol,5,8,13,13a-tetrahydro-10-methoxy-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin- 9-ol,5,8,13,13a-tetrahydro-10-methoxy-

Chemical Property:

Melting Point:183-185°
PSA：51.16000
LogP:2.72290

Purity/Quality:: 99% (HPLC) ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin- 9-ol,5,8,13,13a-tetrahydro-10-methoxy-

There total 22 articles about 6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin- 9-ol,5,8,13,13a-tetrahydro-10-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1429118-98-8
14-(R)-9-benzyloxy-2,3-methylenedioxy-10-methoxytetrahyrdooxyprotoberberine

: 572-76-9,6724-39-6,6808-56-6,17388-17-9
5,6,13,14-tetrahydro-9-hydroxy-10-methoxy-2,3-(methylenedioxy)-8H-dibenzo[a,g]quinolizine

Guidance literature:: With hydrogenchloride; In ethanol; water; for 2h; Reflux;
DOI:10.1016/j.bmc.2012.12.016

Reference yield:

: 15401-69-1
berberrubine chloride

: 572-76-9,6724-39-6,6808-56-6,17388-17-9
5,6,13,14-tetrahydro-9-hydroxy-10-methoxy-2,3-(methylenedioxy)-8H-dibenzo[a,g]quinolizine

Guidance literature:: With methanol; sodium tetrahydroborate; at 60 ℃; for 0.25h;

Reference yield:

: 633-65-8
berberine chloride

: 572-76-9,6724-39-6,6808-56-6,17388-17-9
5,6,13,14-tetrahydro-9-hydroxy-10-methoxy-2,3-(methylenedioxy)-8H-dibenzo[a,g]quinolizine

Guidance literature:: Multi-step reaction with 4 steps

1.1: 0.25 h / 195 °C

1.2: 1 h / 20 °C

2.1: sodium tetrahydroborate / methanol / 20 °C / Reflux

3.1: ethanol

4.1: ammonium hydroxide

With sodium tetrahydroborate; ammonium hydroxide; In methanol; ethanol;
DOI:10.1016/j.bmc.2012.11.002