1H-Pyrazole-3-carboximidamide, 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-N-hydroxy-4-[(trifluoro methyl)sulfinyl]-

Base Information

• Chemical Name: 1H-Pyrazole-3-carboximidamide, 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-N-hydroxy-4-[(trifluoro methyl)sulfinyl]-
• CAS No.: 194941-33-8
• Molecular Formula: C12H7Cl2F6N5O2S
• Molecular Weight: 470.182
• Mol file: 194941-33-8.mol

Synonyms:

Chemical Property of 1H-Pyrazole-3-carboximidamide, 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-N-hydroxy-4-[(trifluoro methyl)sulfinyl]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1H-Pyrazole-3-carboximidamide, 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-N-hydroxy-4-[(trifluoro methyl)sulfinyl]-

There total 2 articles about 1H-Pyrazole-3-carboximidamide, 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-N-hydroxy-4-[(trifluoro methyl)sulfinyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

fipronil (120068-37-3) → 5-amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfinyl-3-pyrazolecarboxamide oxime (194941-33-8)

Guidance literature:

With hydroxylamine hydrochloride; triethylamine; In 1,4-dioxane; water;

Reference yield:

5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-trifluoromethylsulfinyl-1H-pyrazole-3-carboximidic acid methyl ester (209966-79-0) + hydroxylamine hydrochloride (5470-11-1) → 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-N-hydroxy-4-trifluoro-methylsulfinyl-1H-pyrazole-3-carboximidamide (194941-33-8)

Guidance literature:

Reference yield: 40.0%

5-amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfinyl-3-pyrazolecarboxamide oxime (194941-33-8) → 5-amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-3-(4H-1,2,4-oxadiazolin-3-yl)-4-trifluoromethylsulfinylpyrazole (194942-26-2)

Guidance literature:

With formaldehyd; acetic acid; In ethyl acetate; acetonitrile;

upstream raw materials:

fipronil

5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-trifluoromethylsulfinyl-1H-pyrazole-3-carboximidic acid methyl ester

hydroxylamine hydrochloride

Downstream raw materials:

5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-3-(5-oxo-4H-1,2,4-oxadiazolin-3-yl)-4-trifluoromethylsulfinylpyrazole

5-amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-3-(4H-1,2,4-oxadiazolin-3-yl)-4-trifluoromethylsulfinylpyrazole

Refernces

• 1、 -. "Arylpyrazole insecticides". . . Retrieved 2008/06/13.