2-Hydroxy-1-[4-(methylsulfonyl)phenyl]-1-ethanone

Base Information

Chemical Name:2-Hydroxy-1-[4-(methylsulfonyl)phenyl]-1-ethanone
CAS No.:197240-27-0
Molecular Formula:C9H10O4S
Molecular Weight:214.242
Hs Code.:2914700090
DSSTox Substance ID:DTXSID90377031
Wikidata:Q82166051
Mol file:197240-27-0.mol

Synonyms:197240-27-0;2-Hydroxy-1-[4-(methylsulfonyl)phenyl]-1-ethanone;2-Hydroxy-1-(4-(methylsulfonyl)phenyl)ethanone;2-hydroxy-1-(4-methylsulfonylphenyl)ethanone;2-Hydroxy-4'-(methylsulfonyl)acetophenone;MFCD06200929;2-HYDROXY-4-(METHYLSULFONYL)ACETOPHENONE;SCHEMBL5058142;DTXSID90377031;XHA24027;AC5150;AKOS005070141;SY130955;2-Hydroxy-4'-(methylsulphonyl)acetophenone;CS-0449150;1X-0706;2-hydroxy-1-(4-methanesulfonylphenyl)ethan-1-one;A919536;2-Hydroxy-1-(4-(methylsulfonyl)phenyl)ethan-1-one;J-509600;2-Hydroxy-1-[4-(methanesulfonyl)phenyl]ethan-1-one;2-Hydroxy-4 inverted exclamation mark -(methylsulfonyl)acetophenone

Suppliers and Price of 2-Hydroxy-1-[4-(methylsulfonyl)phenyl]-1-ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Hydroxy-1-[4-(methylsulfonyl)phenyl]-1-ethanone
500mg
$ 310.00

SynQuest Laboratories
2-Hydroxy-4'-(methylsulfonyl)acetophenone
1 g
$ 116.00

Matrix Scientific
2-Hydroxy-1-[4-(methylsulfonyl)phenyl]-1-ethanone >95%
5g
$ 455.00

Matrix Scientific
2-Hydroxy-1-[4-(methylsulfonyl)phenyl]-1-ethanone >95%
1g
$ 130.00

Matrix Scientific
2-Hydroxy-1-[4-(methylsulfonyl)phenyl]-1-ethanone >95%
500mg
$ 85.00

Crysdot
2-Hydroxy-1-(4-(methylsulfonyl)phenyl)ethanone 95+%
5g
$ 525.00

Apolloscientific
2-Hydroxy-4'-(methylsulphonyl)acetophenone
1g
$ 105.00

American Custom Chemicals Corporation
2-HYDROXY-4'-(METHYLSULPHONYL)ACETOPHENONE 95.00%
5G
$ 1216.45

American Custom Chemicals Corporation
2-HYDROXY-4'-(METHYLSULPHONYL)ACETOPHENONE 95.00%
1G
$ 711.39

Alichem
2-Hydroxy-1-(4-(methylsulfonyl)phenyl)ethanone
5g
$ 449.40

Total 9 raw suppliers

Chemical Property of 2-Hydroxy-1-[4-(methylsulfonyl)phenyl]-1-ethanone

Chemical Property:

Melting Point:136～138℃
PSA：79.82000
LogP:1.34590
XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:214.02997997
Heavy Atom Count:14
Complexity:293

Purity/Quality:

97% ^*data from raw suppliers

2-Hydroxy-1-[4-(methylsulfonyl)phenyl]-1-ethanone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CS(=O)(=O)C1=CC=C(C=C1)C(=O)CO

Technology Process of 2-Hydroxy-1-[4-(methylsulfonyl)phenyl]-1-ethanone

There total 2 articles about 2-Hydroxy-1-[4-(methylsulfonyl)phenyl]-1-ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 50413-24-6
2-bromo-1-(4-methanesulfonylphenyl)ethanone

: 197240-27-0
α-hydroxy-4'-methanesulfonylacetophenone

Guidance literature:: 2-bromo-1-(4-methanesulfonylphenyl)ethanone; With betaine; In ethanol; at 50 ℃; for 2h;

With sodium hydrogencarbonate; at 20 ℃; for 0.25h; Further stages.;
DOI:10.1021/jm991106b

Reference yield:

: 10297-73-1
4-(methanesulfonyl)acetophenone

: 197240-27-0
α-hydroxy-4'-methanesulfonylacetophenone

Guidance literature:: Multi-step reaction with 2 steps

1.1: 77 percent / Br₂ / CHCl₃ / 1 h / -5 °C

2.1: betaine / ethanol / 2 h / 50 °C

2.2: 87 percent / aq. NaHCO₃ / 0.25 h / 20 °C

With betaine; bromine; In ethanol; chloroform; 1.1: Bromination / 2.1: Substitution / 2.2: Hydrolysis;
DOI:10.1021/jm991106b

Reference yield: 93.0%

: 1333483-14-9
N-methyll-N-(phenylethylnyl)methanesulfonamide

: 197240-27-0
α-hydroxy-4'-methanesulfonylacetophenone

: N-methyl-N-(4-(4-(methylsulfonyl)phenyl)-3-phenylfuran-2-yl)methanesulfonamide

Guidance literature:: With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at 20 ℃; Inert atmosphere;
DOI:10.1002/adsc.202100769