Ethanone, 2-(benzoyloxy)-2-(3,5-dimethoxyphenyl)-1-phenyl-

Base Information

• Chemical Name: Ethanone, 2-(benzoyloxy)-2-(3,5-dimethoxyphenyl)-1-phenyl-
• CAS No.: 198345-21-0
• Molecular Formula: C23H20O5
• Molecular Weight: 376.409
• DSSTox Substance ID: DTXSID80435139
• Nikkaji Number: J918.490B
• Mol file: 198345-21-0.mol

Synonyms:Ethanone, 2-(benzoyloxy)-2-(3,5-dimethoxyphenyl)-1-phenyl-;198345-21-0;DTXSID80435139;Benzoic acid alpha-(3,5-dimethoxyphenyl)-beta-oxophenethyl ester

Chemical Property of Ethanone, 2-(benzoyloxy)-2-(3,5-dimethoxyphenyl)-1-phenyl-

Chemical Property:

• XLogP3: 4.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 8
• Exact Mass: 376.13107373
• Heavy Atom Count: 28
• Complexity: 495

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=CC(=C1)C(C(=O)C2=CC=CC=C2)OC(=O)C3=CC=CC=C3)OC

Technology Process of Ethanone, 2-(benzoyloxy)-2-(3,5-dimethoxyphenyl)-1-phenyl-

There total 2 articles about Ethanone, 2-(benzoyloxy)-2-(3,5-dimethoxyphenyl)-1-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

3,5-dimethoxybenzaldehdye (7311-34-4) + benzil (134-81-6) → 1-(3,5-dimethoxyphenyl)-2-oxo-2-phenylethyl benzoate (198345-21-0)

Guidance literature:

With potassium cyanide; In N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2004.03.016

Reference yield: 57.0%

2-(3,5-dimethoxyphenyl)-2-hydroxy-1-phenylethan-1-one (34904-92-2) + benzoic acid anhydride (93-97-0) → 1-(3,5-dimethoxyphenyl)-2-oxo-2-phenylethyl benzoate (198345-21-0)

Guidance literature:

With pyridine; In dichloromethane; at 20 ℃;

DOI:10.1562/2006-02-07-RA-798

Reference yield: 85.0%

1-(3,5-dimethoxyphenyl)-2-oxo-2-phenylethyl benzoate (198345-21-0) → 2-(3,5-dimethoxyphenyl)-2-hydroxy-1-phenylethan-1-one (34904-92-2)

Guidance literature:

With sodium hydroxide; In water; acetonitrile; for 0.5h; Heating;

DOI:10.1016/j.tet.2004.03.016

upstream raw materials:

3,5-dimethoxybenzaldehdye

benzil

2-(3,5-dimethoxyphenyl)-2-hydroxy-1-phenylethan-1-one

benzoic acid anhydride

Downstream raw materials:

5,7-Dimethoxy-2-phenylbenzofuran

benzoic acid

C₁₆H₁₅O₃⁽¹⁺⁾

2-(3,5-dimethoxyphenyl)-2-hydroxy-1-phenylethan-1-one