4-(Chloromethyl)-2-(4-methylphenyl)-1,3-thiazole

Base Information

Chemical Name:4-(Chloromethyl)-2-(4-methylphenyl)-1,3-thiazole
CAS No.:35199-18-9
Molecular Formula:C11H10 Cl N S
Molecular Weight:223.726
Hs Code.:2934100090
DSSTox Substance ID:DTXSID80366297
Wikidata:Q82151437
Mol file:35199-18-9.mol

Synonyms:4-(chloromethyl)-2-(4-methylphenyl)-1,3-thiazole;35199-18-9;4-(CHLOROMETHYL)-2-(P-TOLYL)THIAZOLE;4-Chloromethyl-2-p-tolyl-thiazole;SODIUMMETAPHOSPHATE;SCHEMBL201539;DTXSID80366297;MOMKYJPSVWEWPM-UHFFFAOYSA-N;2-(p-tolyl)-4-chloromethylthiazole;BBL016932;MFCD03423391;STK437056;AKOS000320865;AB14536;EN300-34117

Suppliers and Price of 4-(Chloromethyl)-2-(4-methylphenyl)-1,3-thiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(chloromethyl)-2-(4-methylphenyl)-1,3-thiazole
50mg
$ 45.00

Matrix Scientific
4-(Chloromethyl)-2-(4-methylphenyl)-1,3-thiazole
500mg
$ 189.00

Crysdot
4-(Chloromethyl)-2-(p-tolyl)thiazole 95+%
5g
$ 594.00

Biosynth Carbosynth
4-(Chloromethyl)-2-(4-methylphenyl)-1,3-thiazole
1 g
$ 255.00

Biosynth Carbosynth
4-(Chloromethyl)-2-(4-methylphenyl)-1,3-thiazole
500 mg
$ 150.00

Biosynth Carbosynth
4-(Chloromethyl)-2-(4-methylphenyl)-1,3-thiazole
250 mg
$ 85.00

Biosynth Carbosynth
4-(Chloromethyl)-2-(4-methylphenyl)-1,3-thiazole
2 g
$ 434.00

Biosynth Carbosynth
4-(Chloromethyl)-2-(4-methylphenyl)-1,3-thiazole
5 g
$ 868.00

American Custom Chemicals Corporation
4-(CHLOROMETHYL)-2-(4-METHYLPHENYL)-1,3-THIAZOLE 95.00%
5G
$ 1168.42

American Custom Chemicals Corporation
4-(CHLOROMETHYL)-2-(4-METHYLPHENYL)-1,3-THIAZOLE 95.00%
2.5G
$ 983.88

Total 7 raw suppliers

Chemical Property of 4-(Chloromethyl)-2-(4-methylphenyl)-1,3-thiazole

Chemical Property:

Vapor Pressure:5.2E-05mmHg at 25°C
Boiling Point:358.6°Cat760mmHg
Flash Point:170.7°C
PSA：41.13000
Density:1.233g/cm³
LogP:3.85730
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:223.0222482
Heavy Atom Count:14
Complexity:180

Purity/Quality:

98% ^*data from raw suppliers

4-(chloromethyl)-2-(4-methylphenyl)-1,3-thiazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=NC(=CS2)CCl

Technology Process of 4-(Chloromethyl)-2-(4-methylphenyl)-1,3-thiazole

There total 5 articles about 4-(Chloromethyl)-2-(4-methylphenyl)-1,3-thiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 2362-62-1
4-methylthiobenzamide

: 534-07-6
1,3-Dichloroacetone

: 35199-18-9
4-chloromethyl-2-(4-methyl-phenyl)-thiazole

Guidance literature:: In toluene; Reflux;
DOI:10.1021/jm401643m

Reference yield:

: 104-85-8
para-methylbenzonitrile

: 35199-18-9
4-chloromethyl-2-(4-methyl-phenyl)-thiazole

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine; triethylamine; diammonium sulfide / water / 50 °C

2: toluene / Reflux

With pyridine; diammonium sulfide; triethylamine; In water; toluene;
DOI:10.1021/jm401643m

Reference yield:

: 99-94-5
p-Toluic acid

: 35199-18-9
4-chloromethyl-2-(4-methyl-phenyl)-thiazole

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride / dichloromethane / Reflux

2: tetraphosphorus decasulfide

3: ethanol; tetrahydrofuran / 6 h / 65 °C

With thionyl chloride; tetraphosphorus decasulfide; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1016/j.ejmech.2018.02.036