[(4-Methylphenyl)(nitroso)amino]acetic acid

Base Information

Chemical Name:[(4-Methylphenyl)(nitroso)amino]acetic acid
CAS No.:52827-02-8
Molecular Formula:C9H10N2O3
Molecular Weight:194.19
Hs Code.:
NSC Number:121386
DSSTox Substance ID:DTXSID90298196
Nikkaji Number:J1.078.016K
Wikidata:Q82039851
Mol file:52827-02-8.mol

Synonyms:52827-02-8;[(4-methylphenyl)(nitroso)amino]acetic acid;NSC121386;DTXSID90298196;N-nitroso-N-(4-methylphenyl)glycine;NSC-121386

Suppliers and Price of [(4-Methylphenyl)(nitroso)amino]acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of [(4-Methylphenyl)(nitroso)amino]acetic acid

Chemical Property:

Vapor Pressure:2.64E-08mmHg at 25°C
Boiling Point:434.1°Cat760mmHg
Flash Point:216.3°C
Density:1.24g/cm³
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:194.06914219
Heavy Atom Count:14
Complexity:212

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)N(CC(=O)O)N=O

Technology Process of [(4-Methylphenyl)(nitroso)amino]acetic acid

There total 4 articles about [(4-Methylphenyl)(nitroso)amino]acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 21911-69-3
N-(p-tolyl)glycine

: 52827-02-8
2-(nitroso(p-tolyl)amino)acetic acid

Guidance literature:: With isopentyl nitrite; In tetrahydrofuran; at 25 ℃; for 2h; Time;
DOI:10.1021/jo501420r

Reference yield:

: 106-49-0,12221-03-3
p-toluidine

: 52827-02-8
2-(nitroso(p-tolyl)amino)acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium acetate / ethanol / Reflux

2.1: lithium hydroxide / tetrahydrofuran; water / 2 h / 2 °C

2.2: 20 °C / pH 3 - 4

3.1: sodium nitrite / water / 0.33 h / 0 °C

With sodium acetate; lithium hydroxide; sodium nitrite; In tetrahydrofuran; ethanol; water;
DOI:10.1021/jo201605v

Reference yield:

: 21911-68-2
ethyl 2-(p-tolylamino)acetate

: 52827-02-8
2-(nitroso(p-tolyl)amino)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium hydroxide / tetrahydrofuran; water / 2 h / 2 °C

1.2: 20 °C / pH 3 - 4

2.1: sodium nitrite / water / 0.33 h / 0 °C

With lithium hydroxide; sodium nitrite; In tetrahydrofuran; water;
DOI:10.1021/jo201605v