21911-68-2

Basic information

• Product Name: ethyl [(4-methylphenyl)amino]acetate
• Synonyms: ethyl [(4-methylphenyl)amino]acetate;2-[(4-methylphenyl)amino]acetic acid ethyl ester;ethyl 2-[(4-methylphenyl)amino]ethanoate
• CAS NO: 21911-68-2
• Molecular Formula: C₁₁H₁₅NO₂
• Molecular Weight: 193.2423
• Mol File: 21911-68-2.mol
• Article Data: 66

Chemical Properties

• Boiling Point: 287.6±15.0 °C(Predicted)
• Appearance: /
• Density: 1.084±0.06 g/cm3(Predicted)
• PKA: 1.98±0.50(Predicted)
• CAS DataBase Reference: ethyl [(4-methylphenyl)amino]acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl [(4-methylphenyl)amino]acetate(21911-68-2)
• EPA Substance Registry System: ethyl [(4-methylphenyl)amino]acetate(21911-68-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 21911-68-2(Hazardous Substances Data)

Upstream product

• 106-49-0 p-toluidine 
• 105-39-5 chloroacetic acid ethyl ester 
• 623-73-4 diazoacetic acid ethyl ester 
• 105-36-2 ethyl bromoacetate 
• 16596-03-5 N,N'-di-p-tolylformamidine 
• 109-92-2 ethyl vinyl ether 
• 106-38-7 para-bromotoluene 
• 77442-80-9 α-bromoethyl acetate 
• 62-53-3 aniline 
• 924-44-7 glyoxylic acid ethyl ester 
• 64-17-5 ethanol 
• 21911-69-3 N-(p-tolyl)glycine 

Downstream Products

• 21911-69-3 N-(p-tolyl)glycine 
• 2350-99-4 2-[(4-methylphenyl)amino]acetohydrazide 
• 92516-06-8 5-mercapto-4-phenyl-3-(N-p-tolylamino)methyl-1,2,4-triazole 
• 92515-98-5 4-phenyl-1-(N-p-tolylamino)acetyl thiosemicarbazide 
• 84827-48-5 N-carbobenzyloxy-L-alanyl-N-(4-methylphenyl)-glycine 
• 142503-68-2 4-Amino-5-(p-tolylamino-methyl)-4H-[1,2,4]triazole-3-thiol 
• 142503-75-1 4-{[1-Phenyl-meth-(E)-ylidene]-amino}-5-(p-tolylamino-methyl)-4H-[1,2,4]triazole-3-thiol 
• 142503-76-2 5-(p-Tolylamino-methyl)-4-{[1-p-tolyl-meth-(E)-ylidene]-amino}-4H-[1,2,4]triazole-3-thiol 

Relevant articles and documents

Reaction of Symmetric N1 ,N2-Diarylamidines with α-Bromoacetophenone and Ethyl 2-Bromoethanoate

2-Bromo-1-{aryl[1-(arylimino)ethyl]amino}-1-phenylethanol derivatives 3a, 3b were obtained from the reaction of N1 ,N2-diarylacetamidines 1a, 1b with α-bromoacetophenone 2, while 1a, 1b with ethyl 2-bromoethanoate 4 afforded 2-{[1-(arylimino)]ethyl}aminoethanoic acid derivatives 5a, 5b; N1,N2-diarylformamidines 6a, 6b reacted with 2 and 4 to give the arylaminoacetophenones 8a, 8b and N-arylglycine ethyl esters 11a, 11b respectively together with the corresponding formanilides 9a, 9b.

Insertion of ethyl diazoacetate into N-H and S-H bonds catalyzed by ruthenium porphyrin complexes

Ruthenium porphyrin complexes catalyze insertion of ethyl diazoacetate into sulfur-hydrogen and nitrogen-hydrogen bonds under mild conditions and with reasonable to very good yields.

Perovskite as Recyclable Photocatalyst for Annulation Reaction of N-Sulfonyl Ketimines

A sustainable and cost-effective manner for the photocatalytic annulation reaction of N-sulfonyl ketimines with N-arylglycines to synthesize imidazolidine-fused sulfamidates (31 examples) by employing CsPbBr3 as a heterogeneous photocatalyst has been developed. The catalyst CsPbBr3 can be simply recovered from the reaction mixture and reused at least five times without an obvious reduction in its photocatalytic reactivity, exhibiting a high catalyst economic feature.

Tunable Redox Potential Photocatalyst: Aggregates of 2,3-Dicyanopyrazino Phenanthrene Derivatives for the Visible-Light-Induced α-Allylation of Amines

This work highlights the tunable redox potential of 6,11-dibromo-2,3-dicyanopyrazinophenanthrene (DCPP3) aggregates, which can be formed through physical π-πstacking interactions with other DCPP3 monomers. Electrochemical and scanning electron microscopy showed that the reduction potential of [DCPP3]n aggregates could be increased by decreasing their size. The size of [DCPP3]n aggregates could be regulated by controlling the concentration of DCPP3 in an organic solvent. As such, a fundamental understanding of this tunable redox potential is essential for developing new materials for photocatalytic applications. The [DCPP3]n aggregates as a visible-light photocatalyst in combination with Pd catalysts in the visible-light-induced α-allylation of amines were used. This [DCPP3]n photocatalyst exhibits excellent photo- and electrochemical properties, including a remarkable visible-light absorption, long excited-state lifetime (16.6 μs), good triplet quantum yield (0.538), and high reduction potential (Ered([DCPP3]n/[DCPP3]n-) > -1.8 V vs SCE).