4-Iodo-4',4''-dimethoxytriphenylamine

Base Information

• Chemical Name: 4-Iodo-4',4''-dimethoxytriphenylamine
• CAS No.: 201802-15-5
• Molecular Formula: C20H18INO2
• Molecular Weight: 431.273
• Mol file: 201802-15-5.mol

Synonyms:4-Iodo-N,N-bis(4-methoxyphenyl)aniline;I0776;4-Iodo-4',4''-diMethoxytriphenylaMine;Benzenamine,4-iodo-N,N-bis(4-methoxyphenyl);

Chemical Property of 4-Iodo-4',4''-dimethoxytriphenylamine

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 109.0 to 113.0 °C
• Boiling Point: 511.917oC at 760 mmHg
• Flash Point: 263.398oC
• PSA: 21.70000
• Density: 1.484g/cm3
• LogP: 5.77820

Purity/Quality:

97% ^*data from raw suppliers

4-Iodo-N,N-bis(4-methoxyphenyl)aniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Iodo-4',4''-dimethoxytriphenylamine

There total 10 articles about 4-Iodo-4',4''-dimethoxytriphenylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.4%

N,N-bis(4-methoxyphenyl)aniline (20440-94-2) → N,N-bis(4-methoxyphenyl)-4'-iodophenylamine (201802-15-5)

Guidance literature:

With N-iodo-succinimide; In N,N-dimethyl-formamide; at 20 ℃; for 23h; Inert atmosphere;

Reference yield: 59.0%

4-bromo-N,N-bis-(4-methoxyphenyl)aniline (194416-45-0) → N,N-bis(4-methoxyphenyl)-4'-iodophenylamine (201802-15-5)

Guidance literature:

4-bromo-N,N-bis-(4-methoxyphenyl)aniline; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Schlenk technique; Inert atmosphere;

With iodine; In tetrahydrofuran; hexane; at -78 ℃; for 3h; Schlenk technique; Inert atmosphere;

DOI:10.1002/ejoc.201900026

Reference yield:

para-iodoanisole (696-62-8) → N,N-bis(4-methoxyphenyl)-4'-iodophenylamine (201802-15-5)

Guidance literature:

Multi-step reaction with 2 steps

1: copper(I) iodide; 1,7-phenanthroline; potassium hydroxide / toluene / Inert atmosphere; Reflux

2: potassium iodide; potassium iodate / acetic acid / Inert atmosphere; Reflux

With potassium iodate; copper(I) iodide; 1,7-phenanthroline; potassium iodide; potassium hydroxide; In acetic acid; toluene; 1: |Ullmann Condensation;

DOI:10.1016/j.ultsonch.2014.05.016

upstream raw materials:

N,N-bis(4-methoxyphenyl)aniline

para-iodoanisole

aniline

bis(4-methoxyphenyl)amine

Downstream raw materials:

(5,15-bis(4-(N,N-bis(4-methoxyphenyl)amino)phenylethynyl)-10,20-dimesitylporphyrinato)zinc(II)

N,N'-bis(4-methoxyphenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline