4-bromo-N,N-bis(4-methoxyphenyl)aniline

Base Information

• Chemical Name: 4-bromo-N,N-bis(4-methoxyphenyl)aniline
• CAS No.: 194416-45-0
• Molecular Formula: C20H18BrNO2
• Molecular Weight: 384.272
• European Community (EC) Number: 808-004-1
• Nikkaji Number: J2.112.797C
• Mol file: 194416-45-0.mol

Synonyms:4-bromo-N,N-bis(4-methoxyphenyl)aniline;194416-45-0;N-(4-bromophenyl)-4-methoxy-N-(4-methoxyphenyl)aniline;4-Bromo-4',4''-dimethoxytriphenylamine;YSWG841;SCHEMBL578301;Di-p-anisyl-p-bromophenylamine;XXCDCFFPMMCPEE-UHFFFAOYSA-N;MFCD22124385;AS-40227;N,N-Bis(4-methoxyphenyl)-4-bromoaniline;4-bromo-N,N-bis(4-methoxyphenyl) aniline;B4667;4-Bromo-4' ,4' -dimethoxyltriphenylamine;A880200;J-400921

Chemical Property of 4-bromo-N,N-bis(4-methoxyphenyl)aniline

Chemical Property:

• Melting Point: 96-98℃
• Boiling Point: 494.6±40.0 °C(Predicted)
• PKA: -2.37±0.50(Predicted)
• PSA: 21.70000
• Density: 1.349±0.06 g/cm3 (20 oC 760 Torr)
• LogP: 5.93610
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 5.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 383.05209
• Heavy Atom Count: 24
• Complexity: 333

Purity/Quality:

99.00% ^*data from raw suppliers

4-Bromo-N,N-bis(4-methoxyphenyl)aniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)N(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)Br

Technology Process of 4-bromo-N,N-bis(4-methoxyphenyl)aniline

There total 16 articles about 4-bromo-N,N-bis(4-methoxyphenyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N,N-bis(4-methoxyphenyl)aniline (20440-94-2) → 4-bromo-N,N-bis-(4-methoxyphenyl)aniline (194416-45-0)

Guidance literature:

With N-Bromosuccinimide; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield: 91.0%

para-iodoanisole (696-62-8) + 4-bromo-aniline (106-40-1) → 4-bromo-N,N-bis-(4-methoxyphenyl)aniline (194416-45-0)

Guidance literature:

With 1,10-Phenanthroline; copper(l) chloride; potassium hydroxide; In toluene; for 16h; Dean-Stark; Reflux;

DOI:10.1021/acs.orglett.6b01539

Reference yield: 88.0%

1,4-bromoiodobenzene (589-87-7) + bis(4-methoxyphenyl)amine (101-70-2) → 4-bromo-N,N-bis-(4-methoxyphenyl)aniline (194416-45-0)

Guidance literature:

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; 1,1'-bis(diphenylphosphino)ferrocene; sodium t-butanolate; In toluene; at 75 - 90 ℃;

DOI:10.1021/ja0511570

upstream raw materials:

N,N-bis(4-methoxyphenyl)aniline

methanol

tri(p-bromophenyl)amine

1,4-bromoiodobenzene

Downstream raw materials:

N³,N³,N^4',N^4'-Tetrakis-(4-methoxy-phenyl)-biphenyl-3,4'-diamine

4-[bis(4-methoxyphenyl)amino]benzaldehyde

4-methoxy-N-(4-methoxyphenyl)-N-(4-(thiophen-2-yl)phenyl)aniline

dimethyl 4-(bis(4-methoxyphenyl)amino)phenylboronate