Oxiranecarboxamide, 2-butyl-N,N-diethyl-3-phenyl-

Base Information

• Chemical Name: Oxiranecarboxamide, 2-butyl-N,N-diethyl-3-phenyl-
• CAS No.: 202478-86-2
• Molecular Formula: C17H25NO2
• Molecular Weight: 275.391
• DSSTox Substance ID: DTXSID50477102
• Nikkaji Number: J1.915.146H
• Mol file: 202478-86-2.mol

Synonyms:Oxiranecarboxamide, 2-butyl-N,N-diethyl-3-phenyl-;202478-86-2;DTXSID50477102

Chemical Property of Oxiranecarboxamide, 2-butyl-N,N-diethyl-3-phenyl-

Chemical Property:

• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 7
• Exact Mass: 275.188529040
• Heavy Atom Count: 20
• Complexity: 321

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCC1(C(O1)C2=CC=CC=C2)C(=O)N(CC)CC

Technology Process of Oxiranecarboxamide, 2-butyl-N,N-diethyl-3-phenyl-

There total 2 articles about Oxiranecarboxamide, 2-butyl-N,N-diethyl-3-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

benzaldehyde (100-52-7) + 2-Chloro-hexanoic acid diethylamide (202478-81-7) → 2-butyl-2,3-epoxy-N,N-diethyl-3-phenylpropanamide (202478-86-2)

Guidance literature:

2-Chloro-hexanoic acid diethylamide; With potassium hexamethylsilazane; In tetrahydrofuran; toluene; at -78 ℃; for 0.166667h;

benzaldehyde; In tetrahydrofuran; toluene; at -78 - 25 ℃;

DOI:10.1021/jo0349577

Reference yield:

N,N-diethyldichloroacetamide (921-88-0) + lithium tri-n-butylmanganate + benzaldehyde (100-52-7) → 2-butyl-2,3-epoxy-N,N-diethyl-3-phenylpropanamide (202478-86-2) + 2-Chloro-2-(hydroxy-phenyl-methyl)-hexanoic acid diethylamide

Guidance literature:

With lithium diisopropyl amide; Yield given. Multistep reaction. Yields of byproduct given;

DOI:10.1021/jo971964k

Reference yield: 87.0%

2-butyl-2,3-epoxy-N,N-diethyl-3-phenylpropanamide (202478-86-2) → (Z)-2-butyl-N,N-diethyl-3-phenylpropenamide

Guidance literature:

With methanol; samarium diiodide; In tetrahydrofuran; at 25 ℃; for 0.5h;

DOI:10.1021/jo0349577

upstream raw materials:

N,N-diethyldichloroacetamide

benzaldehyde

2-Chloro-hexanoic acid diethylamide