1-(2-Bromophenyl)but-2-yn-1-one

Base Information

Chemical Name:1-(2-Bromophenyl)but-2-yn-1-one
CAS No.:207275-14-7
Molecular Formula:C10H7BrO
Molecular Weight:223.069
Hs Code.:
DSSTox Substance ID:DTXSID50578901
Nikkaji Number:J963.135F
Wikidata:Q82469246

Synonyms:1-(2-Bromophenyl)but-2-yn-1-one;207275-14-7;DTXSID50578901

Suppliers and Price of 1-(2-Bromophenyl)but-2-yn-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-(2-Bromophenyl)but-2-yn-1-one

Chemical Property:

PSA：17.07000
LogP:2.65510
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:221.96803
Heavy Atom Count:12
Complexity:233

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC#CC(=O)C1=CC=CC=C1Br

Technology Process of 1-(2-Bromophenyl)but-2-yn-1-one

There total 4 articles about 1-(2-Bromophenyl)but-2-yn-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 429680-29-5
1-(2-bromo-phenyl)-but-2-yn-1-ol

: 207275-14-7
1-(2-Bromo-phenyl)-but-2-yn-1-one

Guidance literature:: With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In dimethyl sulfoxide; at 20 ℃; for 2h;
DOI:10.1002/anie.202013531

Reference yield: 33.0%

: 7154-66-7
2-bromobenzoic acid chloride

: 74-99-7
prop-1-yne

: 207275-14-7
1-(2-Bromo-phenyl)-but-2-yn-1-one

Guidance literature:: With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In benzene; for 15h; Ambient temperature;
DOI:10.1055/s-1998-2062

Reference yield:

: 88-65-3
2-bromobenzoic-acid

: 207275-14-7
1-(2-Bromo-phenyl)-but-2-yn-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂

2: 33 percent / Et₃N / PdCl₂3P>2, CuI / benzene / 15 h / Ambient temperature

With thionyl chloride; triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In benzene;
DOI:10.1055/s-1998-2062