1,2,4,5-Tetrafluoro-3-methoxy-6-(trifluoromethyl)benzene

Base Information

Chemical Name:1,2,4,5-Tetrafluoro-3-methoxy-6-(trifluoromethyl)benzene
CAS No.:20867-94-1
Molecular Formula:C₈H₃F₇O
Molecular Weight:248.1
Hs Code.:2909309090
DSSTox Substance ID:DTXSID30382144
Wikidata:Q82173459
Mol file:20867-94-1.mol

Synonyms:20867-94-1;1,2,4,5-tetrafluoro-3-methoxy-6-(trifluoromethyl)benzene;4-Methoxy-2,3,5,6-tetrafluorobenzotrifluoride;4-Methoxyheptafluorotoluene;MFCD04039294;Benzene, 1,2,4,5-tetrafluoro-3-methoxy-6-(trifluoromethyl)-;SCHEMBL12965171;DTXSID30382144;IZAURIRLQJRFML-UHFFFAOYSA-N;AKOS016015313;2,3,5,6-Tetrafluoro-4-methoxybenzotrifluoride

Suppliers and Price of 1,2,4,5-Tetrafluoro-3-methoxy-6-(trifluoromethyl)benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-METHOXYHEPTAFLUOROTOLUENE 95.00%
100G
$ 3911.12

Total 8 raw suppliers

Chemical Property of 1,2,4,5-Tetrafluoro-3-methoxy-6-(trifluoromethyl)benzene

Chemical Property:

Vapor Pressure:3.58mmHg at 25°C
Refractive Index:1.437
Boiling Point:168-169oC
Flash Point:55oC
PSA：9.23000
Density:1.514g/cm3
LogP:3.27040
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:1
Exact Mass:248.00721185
Heavy Atom Count:16
Complexity:227

Purity/Quality:

99%, ^*data from raw suppliers

4-METHOXYHEPTAFLUOROTOLUENE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C(=C(C(=C1F)F)C(F)(F)F)F)F

Technology Process of 1,2,4,5-Tetrafluoro-3-methoxy-6-(trifluoromethyl)benzene

There total 6 articles about 1,2,4,5-Tetrafluoro-3-methoxy-6-(trifluoromethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: ⁿBu₄N⁺[Cu(2,3,5,6-tetrafluoro-4-methoxylphenyl)(CF₃)₃]^-

: 20867-94-1
4-Trifluoromethyl-2,3,5,6-tetrafluorophenyl methyl ether

Guidance literature:: In 1,2-dichloro-ethane; at 95 ℃; Kinetics; Glovebox; Inert atmosphere;
DOI:10.1002/anie.201904041

Reference yield: 68.0%

: 67-56-1
methanol

: 434-64-0
perfluorotoluene

: 20867-94-1
4-Trifluoromethyl-2,3,5,6-tetrafluorophenyl methyl ether

Guidance literature:: With sodium methylate; for 0.7h; Heating;
DOI:10.1016/S0022-1139(00)00405-X

Reference yield:

: 434-64-0
perfluorotoluene

: 2996-92-1,46143-12-8
phenyl trimethylsiloxane

: 20867-94-1
4-Trifluoromethyl-2,3,5,6-tetrafluorophenyl methyl ether

Guidance literature:: With [Ni₂(1,3-diisopropyl-imidazolin-2-ylidene)₄(μ-1,5-cyclooctadiene)]; tetramethylammonium fluoride; In toluene; at 110 ℃; for 48h; Inert atmosphere;
DOI:10.1002/ejic.201801477