Triethylene Glycol Mono(2-propynyl) Ether

Base Information

Chemical Name:Triethylene Glycol Mono(2-propynyl) Ether
CAS No.:208827-90-1
Molecular Formula:C9H16O4
Molecular Weight:188.224
Hs Code.:
European Community (EC) Number:846-686-2
Nikkaji Number:J2.017.245B
Mol file:208827-90-1.mol

Synonyms:1-O-propargyl triethylene glycol;

Suppliers and Price of Triethylene Glycol Mono(2-propynyl) Ether

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-[2-[2-(2-Propynyloxy)ethoxy]ethoxy]ethanol
5g
$ 795.00

TRC
2-[2-[2-(2-Propynyloxy)ethoxy]ethoxy]ethanol
10g
$ 1425.00

TRC
2-[2-[2-(2-Propynyloxy)ethoxy]ethoxy]ethanol
1g
$ 195.00

TCI Chemical
Triethylene Glycol Mono(2-propynyl) Ether >96.0%(GC)
5g
$ 270.00

TCI Chemical
Triethylene Glycol Mono(2-propynyl) Ether >96.0%(GC)
1g
$ 86.00

purepeg
HC≡C-CH2-PEG3-OH min.97%
5 g
$ 460.00

Medical Isotopes, Inc.
2-[2-[2-(2-Propynyloxy)ethoxy]ethoxy]ethanol
25 g
$ 2120.00

Medical Isotopes, Inc.
2-[2-[2-(2-Propynyloxy)ethoxy]ethoxy]ethanol
2.5 g
$ 640.00

Chem-Impex
Triethyleneglycolmono(2-propynyl)ether,96%(GC) 96%(GC)
1G
$ 84.00

Chem-Impex
Triethyleneglycolmono(2-propynyl)ether,≥96%(GC) ≥96%(GC)
5G
$ 308.67

Total 23 raw suppliers

Chemical Property of Triethylene Glycol Mono(2-propynyl) Ether

Chemical Property:

Refractive Index:1.4610 to 1.4650
Boiling Point:277.2±25.0 °C(Predicted)
PKA:14.36±0.10(Predicted)
PSA：47.92000
Density:1.060±0.06 g/cm3(Predicted)
LogP:-0.33830
Storage Temp.:2-8°C
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
XLogP3:-0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:9
Exact Mass:188.10485899
Heavy Atom Count:13
Complexity:138

Purity/Quality:

99% ^*data from raw suppliers

2-[2-[2-(2-Propynyloxy)ethoxy]ethoxy]ethanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C#CCOCCOCCOCCO
Description Propargyl-PEG4-alcohol is a Click Chemistry reagent that can react with azide-bearing compounds or biomolecules; copper is needed as a catalyst. The PEG units help increase the solubility of the molecule in aqueous media.
Uses 2-[2-[2-(2-Propynyloxy)ethoxy]ethoxy]ethanol is a reactant used in the preparation of bis-sulfide bioconjugates for glutathione triggered tumor responsive drug release.

Technology Process of Triethylene Glycol Mono(2-propynyl) Ether

There total 9 articles about Triethylene Glycol Mono(2-propynyl) Ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 106-96-7
propargyl bromide

: 112-27-6
2,2'-[1,2-ethanediylbis(oxy)]bisethanol

: 208827-90-1
O-propargyl triethylene glycol

Guidance literature:: 2,2'-[1,2-ethanediylbis(oxy)]bisethanol; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 0.25h; Inert atmosphere;

propargyl bromide; In tetrahydrofuran; Inert atmosphere;

Reference yield: 90.0%

: 43113-37-7
tri(ethylene)glycol

: 106-96-7
propargyl bromide

: 208827-90-1
O-propargyl triethylene glycol

Guidance literature:: tri(ethylene)glycol; With potassium tert-butylate; In tetrahydrofuran; at 0 - 25 ℃; for 0.5h; Inert atmosphere;

propargyl bromide; In tetrahydrofuran; at 25 ℃; for 14h; Inert atmosphere;
DOI:10.1021/ja403323y