Clacyfos

Base Information

Chemical Name:Clacyfos
CAS No.:215655-76-8
Molecular Formula:C12H15Cl2O6P
Molecular Weight:357.127
Hs Code.:
UNII:DEP8EV69MY
DSSTox Substance ID:DTXSID50692878
Nikkaji Number:J2.952.832B
ChEMBL ID:CHEMBL2227911

Synonyms:CLACYFOS;Clacyfos [ISO];DEP8EV69MY;215655-76-8;1-(dimethoxyphosphinyl)ethyl 2-(2,4-dichlorophenoxy)acetate;Rac-(1R)-1-(dimethoxyphosphoryl)ethyl (2,4-dichlorophenoxy)acetate;Acetic acid, (2,4-dichlorophenoxy)-, 1-(dimethoxyphosphinyl)ethyl ester;(1RS)-1-(Dimethoxyphosphinoyl)ethyl (2,4-dichlorophenoxy)acetate;Acetic acid, 2-(2,4-dichlorophenoxy)-, 1-(dimethoxyphosphinyl)ethyl ester;UNII-DEP8EV69MY;CHEMBL2227911;SCHEMBL15546253;DTXSID50692878;BDBM50486217;1-(Dimethoxyphosphoryl)ethyl (2,4-dichlorophenoxy)acetate;O,O-dimethyl 1-(2,4-dichlorophenoxyacetoxy)ethylphosphonate;1-[(2,4-Dichlorophenoxy)acetoxy]ethylphosphonic acid dimethyl ester

Suppliers and Price of Clacyfos

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Clacyfos

Chemical Property:

PSA：80.87000
LogP:3.74730
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:355.9983306
Heavy Atom Count:21
Complexity:386

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(OC(=O)COC1=C(C=C(C=C1)Cl)Cl)P(=O)(OC)OC

Technology Process of Clacyfos

There total 3 articles about Clacyfos which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.8%

: 10184-66-4
dimethyl (1-hydroxyethyl)phosphonate

: 774-74-3
2-(2,4-dichlorophenoxy)acetyl chloride

: 215655-76-8
O,O-dimethyl α-(2,4-dichlorophenoxyacetoxy)ethylphosphonate

Guidance literature:: With dmap; triethylamine; In chloroform; toluene; at -40 - -30 ℃; for 4h; Temperature; Solvent; Reagent/catalyst; Autoclave; Large scale;

Reference yield:

: 3757-76-4
sodium 2,4-dichlorophenolate

: 187973-21-3
chloro-acetic acid 1-(dimethoxy-phosphoryl)-ethyl ester

: 215655-76-8
O,O-dimethyl α-(2,4-dichlorophenoxyacetoxy)ethylphosphonate

Guidance literature:: With sodium iodide; In N,N-dimethyl-formamide; at 120 ℃;
DOI:10.1080/10426509908546324

Reference yield:

: 120-83-2,40477-79-0
2,4-dichlorophenol

: 215655-76-8
O,O-dimethyl α-(2,4-dichlorophenoxyacetoxy)ethylphosphonate

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide

2: thionyl chloride

3: pyridine / chloroform / 10 - 42 °C

With pyridine; thionyl chloride; sodium hydroxide; In chloroform;
DOI:10.1021/jf104247w